Evidence map›Paper›PMID 25878771›Full record

ArticleChiropractic & manual therapies2015

Reliability of diagnostic ultrasound in measuring the multifidus muscle.

Eirik Johan Skeie, Jan Arve Borge, Charlotte Leboeuf-Yde, Jenni Bolton, Niels Wedderkopp

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Chiropractic & manual therapies, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06875791 (A Safety and Efficacy Trial of TV5M01 for Radiation-Induced Mucositis in Patients Undergoing Treatment for Head and Neck Cancer), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06875791 phase1 / phase2not yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Safety and Efficacy Trial of TV5M01 for Radiation-Induced Mucositis in Patients Undergoing Treatment for Head and Neck Cancer

TypeinterventionalSponsorFundacion Clinica Valle del LiliRan2025 to 2026Enrolled40ConditionsSquamous Cell Carcinoma of the Head and Neck, Oral MucositisArmsGreen Tea Extract with Morphine, Active Comparator: Triple Mixture Oral Rinse for Radiation-Induced Mucositis
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eirik Johan SkeieMChiro, MSc, Ulriksdal 2, 5009 Bergen, Norway.
Jan Arve BorgeDC, MSc, Ulriksdal 2, 5009 Bergen, Norway.
Charlotte Leboeuf-YdeDepartment Spincenter of Southern Denmark Hospital Lillebælt, Østre Hougvej 55, DK-5500 Middelfart, Denmark.
Jenni BoltonAnglo European College of Chiropractic. Research Department, 13-15 Parkwood Road, Bournemouth BH5 2DF England, UK.
Niels WedderkoppOrthopaedic Department, Center for Spine Surgery, Hospital of Lillebaelt, Institute of Regional Health Service Research and Center for Research in Childhood Health, University of Southern Denmark, Østre Hougvej 55, DK5500 Middelfart, Denmark.
Lerøy (Norway) · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUltrasound is frequently used to measure activity in the lumbar multifidus muscle (LMM). However previous reliability studies on diagnostic ultrasound and LMM have included a limited number of subjects and few have used Bland-Altman's Limits of Agreement (LOA). Further one does not know if activity affects the subjects' ability to contract the LMM.

methodsFrom January 2012 to December 2012 an inter- and intra-examiner reliability study was carried out in a clinical setting. It consisted of a total of four experiments with 30 subjects in each study. Two experienced examiners performed all measurements. Ultrasound measurements were made of: 1. the LMM in the resting state, 2. during a contracted state, 3. on subsequent days, and, before and after walking. Reliability and agreement was tested for 1. resting LMM, 2. contracted LMM, and 3. thickness change in the LMM. Mean values of three measurements were used for statistical analysis for each spinal level. The intra-class correlation coefficient (ICC) 3.1 and 3.2 was used to test for reliability, and Bland-Altman's LOA method to test for agreement.

resultsAll of the studies indicate high levels of reliability, but as the LMM thickness increased (increasing contraction) the agreement between examiners was poorer than for low levels of contraction.

conclusionsThe use of diagnostic ultrasound to measure the LMM seems to be reliable in subjects who have little or no change in thickness of the LMM with contraction.

Indexed as

AgreementDiagnostic ultrasoundIntraclass correlation coefficientLimits of agreementLumbar multifidusMeasurementReliability

Identifiers

PMID25878771
PMCPMC4397671
OpenAlexW2108045181

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.