Evidence map›Paper›PMID 25878649›Full record

ArticlePakistan journal of medical sciences

Differential diagnosis problems in a patient with dysphonia and chronic lymphocytic leukemia.

Gabriela-Ariadna Gavrila, Romeo-Gabriel Mihaila, Ioan Manitiu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gabriela-Ariadna GavrilaGabriela-Ariadna Gavrila, MD, Emergency County Clinical Hospital Sibiu, Corneliu Coposu Avenue, No 2-4, 550245, Sibiu, Romania.
Romeo-Gabriel MihailaRomeo-Gabriel Mihaila, MD, PhD, "Lucian Blaga" University of Sibiu, Faculty of Medicine, Str. Lucian Blaga, nr. 2A, Cod 550169, Sibiu, Romania.
Ioan ManitiuIoan Manitiu, MD, PhD, "Lucian Blaga" University of Sibiu, Faculty of Medicine, Str. Lucian Blaga, nr. 2A, Cod 550169, Sibiu, Romania.
Lucian Blaga University of Sibiu · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysphonia is frequently an expression of laryngitis, especially when it comes in the evolution of an immunosuppressed patient, as happens in chronic lymphoproliferation. But other causes of dysphonia should also not be forgotten, including the possibility of new malignancies, especially due to the fact that these patients have genomic instability that predisposes to appearance of a second or even a third cancer. We present the case of a patient who developed dysphonia during chronic lymphocytic leukemia evolution. Its etiology was a mediastinal compression through lymph nodes, not linked to leukemia, but produced by metastases of a bronchopulmonary cancer, appeared recently. Dysphonia condition due to vocal cord dysfunction must include diseases of the mediastinum, the neck and the brain stem. The rapid and correct diagnosis and the prompt start of an appropriate treatment are of paramount importance for clinician who manage their care and for patient survival.

Indexed as

Chronic lymphocytic leukemiaDysphoniaGenomic instabilityLung cancerMediastinal compression

Identifiers

PMID25878649
PMCPMC4386192
OpenAlexW2320558992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.