ArticlePakistan journal of medical sciences
Expressions and clinical significance of serum bone Gla-protein, bone alkaline phosphatase and C-terminal telopeptide of type I collagen in bone metabolism of patients with osteoporosis.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Effects of short-term step aerobics exercise on bone metabolism and functional fitness in postmenopausal women with low bone mass.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Trial
- Warming acupuncture-moxibustion combined with Bushen Qianggu Recipe effectively improves bone metabolism in osteoporosis patients.American journal of translational research · 2024Article
- Nomogram for predicting reoperation following internal fixation of nondisplaced femoral neck fractures in elderly patients.Journal of orthopaedic surgery and research · 2021Article
- Evaluation of laboratory parameters and symptoms after parathyroidectomy in dialysis patients with secondary hyperparathyroidism.Renal failure · 2019Article
- Establishment of an osteoporosis model in tree shrews by bilateral ovariectomy and comprehensive evaluation.Experimental and therapeutic medicine · 2019Article
- [Value of serum alkaline phosphatase for predicting 2-year fracture in patients with chronic kidney disease on dialysis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018Article
- Abnormal bone mineral density and bone turnover marker expression profiles in patients with primary spontaneous pneumothorax.Journal of thoracic disease · 2016Article
- Changes of Serum Bone Metabolism Indexes and Ultrasonic Bone Mineral Density in Patients with Diabetic Nephropathy at Different Stages and their effects on Diabetic Renal Microvascular Complications.Pakistan journal of medical sciencesArticle
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4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to evaluate the expressions and clinical significance of bone Gla-protein (BGP), bone alkaline phosphatase (B-ALP) and C-terminal telopeptide of type I collagen (CTX) in patients with osteoporosis (OP), and to provide evidence for developing individualized treatment plans.
methodsSeventy-two OP patients in our hospital were selected as an OP group, and another 72 healthy subjects were used as a control group. Their BGP, B-ALP and CTX levels as well as bone mineral density (BMD) values were measured. The correlations between BGP, B-ALP and CTX levels and BMD values were determined.
resultsThe BGP level of the OP group [(5.61±5.52) ng/ml] was significantly higher than that of the control group (P<0.05), but the levels of B-ALP and CTX did not differ significantly (P>0.05). The BMD values of femoral neck and Ward's triangle in the OP group were negatively correlated with the B-ALP levels (P<0.05). For women OP patients, the BMD values of femoral neck and Ward's triangle were also negatively correlated with the B-ALP levels (P<0.05). The BMD of femoral neck in the control group was negatively correlated with the CTX level (P<0.05).
conclusionDetermining BGP, B-ALP and CTX levels can evaluate the bone metabolism degree, which provides evidence for clinical typing of OP and developing treatment strategies.
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