Evidence map›Paper›PMID 25878479›Full record

ArticleJournal of international oral health : JIOH2015

Antigenic heterogeneity in granular cell ameloblastoma: an immunohistochemical study.

Ramadoss Ramya, Peddanna Kondamari Sudheerkanth, Cherian Eapen, Varghese Kumaranthara Alex, Krishnan Rajkumar, Padmanaban Rajashree

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of international oral health : JIOH, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ramadoss RamyaReader, Department of Oral Pathology, SRM Dental College, Chennai, Tamil Nadu, India.
Peddanna Kondamari SudheerkanthReader, Department of Oral Pathology, Mamata Dental College, Khammam, Telangana, India.
Cherian EapenReader, Department of Oral Pathology, St. Gregorius Dental College, Ernakulam, Kerala, India.
Varghese Kumaranthara AlexProfessor, Department of Oral Pathology, Pushpagiri College of Dental Sciences, Thiruvalla, Kerala, India.
Krishnan RajkumarProfessor & Head, Department of Oral Pathology, SRM Dental College, Chennai, Tamil Nadu, India.
Padmanaban RajashreeResearch Faculty, Department of Oral Pathology, SRM Dental College, Chennai, Tamil Nadu, India.
SRM Dental College · INGeneral Hospital Ernakulam · INMamata Medical College · INPushpagiri Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNature of granular cells in granular cell ameloblastoma (GCA) has always invoked considerable interest. The present study aims at antigenic characterization in five such cases with a panel of markers. MATERIALS AND

methodsTissue specimens of five patients with GCA were fixed in buffered formalin and later embedded in paraffin wax. Blocks were sliced into 3 µ thick sections for immunohistochemical analysis using a panel of markers CD68, Bcl2, S100, p53, cytokeratin (AE1/AE3), vimentin and desmin.

resultsAll five cases were strongly positive for cytokeratin and CD68. S100 was negative in three cases and showed a mild positivity in two cases. Bcl2, p53, vimentin and desmin were negative in all the five cases.

conclusionsThis study presents a heterogenous nature of the granular cells; however, further validation is required with a larger sample size.

Indexed as

Bcl2CD68cytokeratin (AE1/AE3)desmingranular cell ameloblastomalysosomesp53S100vimentin

Identifiers

PMID25878479
PMCPMC4385726
OpenAlexW595876902

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LicenceCC BY-NC-SA
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