Evidence map›Paper›PMID 25878473›Full record

ArticleJournal of international oral health : JIOH2015

Epidemiology of Oropharyngeal Candidiasis in Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome Patients and CD4+ Counts.

Antoine Berberi, Ziad Noujeim, Georges Aoun

Open access · greenAbstract read
In one paragraph

Article in Journal of international oral health : JIOH, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. bioRxiv : the preprint server for biology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Frontiers in microbiology · 2020
    Article
  13. Biofilm-ProducingHIV/AIDS (Auckland, N.Z.) · 2020
    Article
  14. Article
  15. Antimicrobial agents and chemotherapy · 2019
    Article
  16. Article
  17. Frontiers in microbiology · 2019
    Article
  18. Infection and drug resistance · 2019
    Article
  19. Importance of various oral manifestations regardless of CD4 cell count in HIV/AIDS patients.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2018
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Antoine BerberiProfessor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut, Lebanon.
Ziad NoujeimLecturer and Director Postgraduate Program of Oral Pathology, Departments of Oral and Maxillofacial Surgery and Pathology and Diagnosis Science, School of Dentistry, Lebanese University, Beirut, Lebanon.
Georges AounAssistant Professor, Department of Pathology and Diagnosis Science, School of Dentistry, Lebanese University, Beirut, Lebanon.
Lebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study was directed to evaluate the forms of oropharyngeal candidiasis (OPC) and their correlation with CD4+ cell counts in human immunodeficiency virus (HIV) patients. MATERIALS AND

methodsThis was a descriptive and analytical cross-sectional study carried out for a 2-year period, in which quantitative data collection methods were used. 50 patients with HIV infection were evaluated. Relationship between OPC and CD4+ was investigated.

resultsFive different clinical forms were noticed on examination: pseudomembranous candidiasis 20/38 (P) was the most common one (52.6%) followed by erythematous 5/38 (13.15%), angular cheilitis 5/38 (13.15%) (AC), a combination of AC and E 4/38 (10.52%) or AC, E and P 4/38 (10.52%). Candida albicans was the most frequent specie isolated in 35 cases of OPC (92%). Candida tropicalis was isolated in 2 cases (5.26%) and Candida glabrata in 1 case (2.64%). The majority of patients with OPC had cell counts 28/38 (73%) <200 cells/mm(3), followed by 9/38 (23%) at CD4+ cell counts of 201-499 cells/mm(3).

conclusionOral Candida colonization and invasive infection occur more frequently in HIV-positive patient and is significantly more common in patients with CD4+ cell counts <200 cell/mm(3).

Indexed as

Acquired immune deficiency syndromecandidiasisCD4+human immunodeficiency virusoral lesions

Identifiers

PMID25878473
PMCPMC4385720
OpenAlexW2145286273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.