Evidence map›Paper›PMID 25878336›Full record

ArticleJournal of clinical microbiology2015

Comparative Evaluation of Two PCR-Based Methods for Detection of Methicillin-Resistant Staphylococcus aureus (MRSA): Xpert MRSA Gen 3 and BD-Max MRSA XT.

Margaux Lepainteur, Sandrine Delattre, Sophie Cozza, Christine Lawrence, Anne-Laure Roux, Martin Rottman

Abstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Characterization of SCCAntimicrobial agents and chemotherapy · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Evolving Rapid Methicillin-resistantJournal of global infectious diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Margaux LepainteurInfection Control Team, Hôpital Raymond Poincaré, AP-HP, Garches, France Microbiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France.
Sandrine DelattreMicrobiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France.
Sophie CozzaMicrobiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France.
Christine LawrenceInfection Control Team, Hôpital Raymond Poincaré, AP-HP, Garches, France Microbiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France.
Anne-Laure RouxMicrobiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France INSERM U1173, UFR Simone Veil, Versailles-Saint-Quentin University, Saint-Quentin en Yvelines, France.
Martin RottmanMicrobiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France INSERM U1173, UFR Simone Veil, Versailles-Saint-Quentin University, Saint-Quentin en Yvelines, France martin.rottman@rpc.aphp.fr.ORCID http://orcid.org/0000-0001-5953-3344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared two walk-away molecular diagnostic assays, the GeneXpert MRSA Gen 3 assay and the BD-Max MRSA XT assay. A total of 119 prospective swabs and 36 culture-positive samples were tested. Xpert MRSA Gen 3 had sensitivity of 95.7% and specificity of 100% versus 87.5% and 97.1% for BD-Max. The difference in agreement with the enriched culture results was significantly in favor of the Xpert assay (P < 0.02, McNemar nonparametric text).

Indexed as

HumansMethicillin-Resistant Staphylococcus aureusMolecular Diagnostic TechniquesNasal CavityPolymerase Chain ReactionProspective StudiesReproducibility of ResultsSensitivity and SpecificityStaphylococcal Infections

Identifiers

PMID25878336
PMCPMC4432069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.