ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Modulation-frequency-specific adaptation in awake auditory cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 25 citations in OpenAlex.
- Differential Myeloarchitecture of Subfields of the Mammalian Auditory Cortex: A Comparative Approach.Brain, behavior and evolution · 2026Review
- Forward masking of amplitude modulation: Sensory versus perceptual components.The Journal of the Acoustical Society of America · 2025Article
- Hierarchical emergence of opponent coding in auditory belt cortex.Journal of neurophysiology · 2025Article
- Receptive-field nonlinearities in primary auditory cortex: a comparative perspective.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Adaptation in auditory processing.Physiological reviews · 2023Review
- A Redundant Cortical Code for Speech Envelope.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Forward masking of spectrotemporal modulation detection.The Journal of the Acoustical Society of America · 2022Article
- Temporally precise population coding of dynamic sounds by auditory cortex.Journal of neurophysiology · 2021Article
- Extracellular voltage thresholds for maximizing information extraction in primate auditory cortex: implications for a brain computer interface.Journal of neural engineering · 2021Article
- Auditory Cortical Plasticity Dependent on Environmental Noise Statistics.Cell reports · 2020Article
- Developmentally Regulated Rebound Depolarization Enhances Spike Timing Precision in Auditory Midbrain Neurons.Frontiers in cellular neuroscience · 2020Article
- Amplitude modulation coding in awake mice and squirrel monkeys.Journal of neurophysiology · 2018Article
- Background noise exerts diverse effects on the cortical encoding of foreground sounds.Journal of neurophysiology · 2017Article
- Cascaded Amplitude Modulations in Sound Texture Perception.Frontiers in neuroscience · 2017Article
- Cluster-based analysis improves predictive validity of spike-triggered receptive field estimates.PloS one · 2017Article
- Comodulation Enhances Signal Detection via Priming of Auditory Cortical Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Effects of Signal-to-Noise Ratio on Auditory Cortical Frequency Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Synaptic plasticity as a cortical coding scheme.Current opinion in neurobiology · 2015Review
- Deviance-Related Responses along the Auditory Hierarchy: Combined FFR, MLR and MMN Evidence.PloS one · 2015Article
- Faster Repetition Rate Sharpens the Cortical Representation of Echo Streams in Echolocating Bats.eNeuroArticle
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
Abstract
Amplitude modulations are fundamental features of natural signals, including human speech and nonhuman primate vocalizations. Because natural signals frequently occur in the context of other competing signals, we used a forward-masking paradigm to investigate how the modulation context of a prior signal affects cortical responses to subsequent modulated sounds. Psychophysical "modulation masking," in which the presentation of a modulated "masker" signal elevates the threshold for detecting the modulation of a subsequent stimulus, has been interpreted as evidence of a central modulation filterbank and modeled accordingly. Whether cortical modulation tuning is compatible with such models remains unknown. By recording responses to pairs of sinusoidally amplitude modulated (SAM) tones in the auditory cortex of awake squirrel monkeys, we show that the prior presentation of the SAM masker elicited persistent and tuned suppression of the firing rate to subsequent SAM signals. Population averages of these effects are compatible with adaptation in broadly tuned modulation channels. In contrast, modulation context had little effect on the synchrony of the cortical representation of the second SAM stimuli and the tuning of such effects did not match that observed for firing rate. Our results suggest that, although the temporal representation of modulated signals is more robust to changes in stimulus context than representations based on average firing rate, this representation is not fully exploited and psychophysical modulation masking more closely mirrors physiological rate suppression and that rate tuning for a given stimulus feature in a given neuron's signal pathway appears sufficient to engender context-sensitive cortical adaptation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.