ArticleJournal of neurophysiology2015
Dynamic dendritic compartmentalization underlies stimulus-specific adaptation in an insect neuron.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Neuronal processing of complex sounds in the prothoracic ganglion of a bushcricket.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Tonotopic CaJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024Article
- Local prothoracic auditory neurons in Ensifera.Frontiers in neuroscience · 2022Article
- Temporal processing properties of auditory DUM neurons in a bush-cricket.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Article
- The Input-Output Relationship of AIY Interneurons in Caenorhabditis elegans in Noisy Environment.iScience · 2019Article
- Differences in Sodium Channel Densities in the Apical Dendrites of Pyramidal Cells of the Electrosensory Lateral Line Lobe.Frontiers in neural circuits · 2019Article
- Dendritic CaJournal of neurophysiology · 2018Article
- Multivariate female preference tests reveal latent perceptual biases.Proceedings. Biological sciences · 2016Article
- Character State Reconstruction of Call Diversity in the Neoconocephalus Katydids Reveals High Levels of Convergence.PLoS currents · 2016Article
- Response recovery in the locust auditory pathway.Journal of neurophysiology · 2016Article
- Direction-Specific Adaptation in Neuronal and Behavioral Responses of an Insect Mechanosensory System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Frequency-specific adaptation and its underlying circuit model in the auditory midbrain.Frontiers in neural circuits · 2015Article
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
In many neural systems, repeated stimulation leads to stimulus-specific adaptation (SSA), with responses to repeated signals being reduced while responses to novel stimuli remain unaffected. The underlying mechanisms of SSA remain mostly hypothetical. One hypothesis is that dendritic processes generate SSA. Evidence for such a mechanism was recently described in an insect auditory interneuron (TN-1 in Neoconocephalus triops). Afferents, tuned to different frequencies, connect with different parts of the TN-1 dendrite. The specific adaptation of these inputs relies on calcium and sodium accumulation within the dendrite, with calcium having a transient and sodium a tonic effect. Using imaging techniques, we tested here whether the accumulation of these ions remained limited to the stimulated parts of the dendrite. Stimulation with a fast pulse rate, which results in strong adaptation, elicited a transient dendritic calcium signal. In contrast, the sodium signal was tonic, remaining high during the fast pulse rate stimulus. These time courses followed the predictions from the previous pharmacological experiments. The peak positions of the calcium and sodium signals differed with the carrier frequency of the stimulus; at 15 kHz, peak locations were significantly more rostral than at 40 kHz. This matched the predictions made from neuroanatomical data. Our findings confirm that excitatory postsynaptic potentials rather than spiking cause the increase of dendritic calcium and sodium concentrations and that these increases remain limited to the stimulated parts of the dendrite. This supports the hypothesis of "dynamic dendritic compartmentalization" underlying SSA in this auditory interneuron.
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