Evidence map›Paper›PMID 25877830›Full record

ReviewGlycoconjugate journal2015

Glycan microarrays of fluorescently-tagged natural glycans.

Xuezheng Song, Jamie Heimburg-Molinaro, David F Smith, Richard D Cummings

Abstract readReview
In one paragraph

Review in Glycoconjugate journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Glycan Array Technology.Advances in biochemical engineering/biotechnology · 2021
    Article
  4. Review
  5. Tools for generating and analyzing glycan microarray data.Beilstein journal of organic chemistry · 2020
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Glycointeractions in bacterial pathogenesis.Nature reviews. Microbiology · 2018
    Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xuezheng SongDepartment of Biochemistry, The National Center for Functional Glycomics, Emory University School of Medicine, Atlanta, GA, 30322, USA. xsong2@emory.edu.
Jamie Heimburg-MolinaroDepartment of Biochemistry, The National Center for Functional Glycomics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
David F SmithDepartment of Biochemistry, The National Center for Functional Glycomics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Richard D CummingsDepartment of Biochemistry, The National Center for Functional Glycomics, Emory University School of Medicine, Atlanta, GA, 30322, USA.

Funding

Overall Priority Score P41GM103694 · NIGMS · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D · 2013 to 2018
$6.9M
NIGMS NIH HHS P41 GM103694NIGMS NIH HHS P41GM103694
6 · The paper itself

Abstract

This review discusses the challenges facing research in 'functional glycomics' and the novel technologies that are being developed to advance the field. The structural complexity of glycans and glycoconjugates makes studies of both their structures and recognition difficult. However, these intricate structures can be captured from their natural sources, isolated and fluorescently-tagged for detailed structural analysis and for presentation on glycan microarrays for functional recognition by glycan-binding proteins. These advances in glycan preparation and manipulation enable the streamlining of functional glycomics studies and will help to propel the field forward in studying natural, biologically relevant glycans.

Indexed as

GlycomicsGlycoconjugatesHumansMicroarray AnalysisPolysaccharidesProtein BindingProteinsGlycoconjugatesPolysaccharidesProteinsFunctional GlycomicsGlycan microarrayGlycansNatural glycansShotgun glycomics

Identifiers

PMID25877830
PMCPMC4607549

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.