Evidence map›Paper›PMID 25877784›Full record

Trial reportCancer2015

Effects of a clinician referral and exercise program for men who have completed active treatment for prostate cancer: A multicenter cluster randomized controlled trial (ENGAGE).

Patricia M Livingston, Melinda J Craike, Jo Salmon, Kerry S Courneya, Cadeyrn J Gaskin, Steve F Fraser, Mohammadreza Mohebbi, Suzanne Broadbent, Mari Botti, Bridie Kent and 1 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05739565 (Title Impact of a Physical Activity Intervention With Motivational Support From Peers for Prostate Cancer Patients - ACTI-PAIR 2 Multicenter, Randomized Stepped-wedge Study), which is not on this map. Cited by 49 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05739565 narecruitingnot on this mapstarted 2023, after this paper: background citation

Title Impact of a Physical Activity Intervention With Motivational Support From Peers for Prostate Cancer Patients - ACTI-PAIR 2 Multicenter, Randomized Stepped-wedge Study

TypeinterventionalSponsorCentre Hospitalier Universitaire de Saint EtienneRan2023 to 2028Enrolled850ConditionsProstate CancerArmsActi-Pair program
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 14 syntheses or guidelines pooled it.

  1. Pooled it
  2. A systematic review and narrative synthesis of physical activity referral schemes' components.The international journal of behavioral nutrition and physical activity · 2023
    Pooled it
  3. Pooled it
  4. Do Patients with Prostate Cancer Benefit from Exercise Interventions? A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Effects of exercise interventions on social and cognitive functioning of men with prostate cancer: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Pooled it
  8. Pooled it
  9. Distress Management, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.Journal of the National Comprehensive Cancer Network : JNCCN · 2019
    Guideline
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Effects of resistance exercise in prostate cancer patients: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Pooled it
  14. Pooled it
  15. Trial
  16. Factors predicting gains in moderate-to-vigorous physical activity in prostate cancer survivors on androgen deprivation therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
  17. Trial
  18. Trial
  19. Mechanisms of Physical Activity Behavior Change for Prostate Cancer Survivors: A Cluster Randomized Controlled Trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2018
    Trial
  20. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Patricia M LivingstonFaculty of Health, Deakin University, Burwood, Australia.
Melinda J CraikeCentre for Social and Early Emotional Development and School of Psychology, Faculty of Health, Deakin University, Burwood, Australia.
Jo SalmonSchool of Exercise and Nutrition Sciences, Faculty of Health, Deakin University, Burwood, Australia.
Kerry S CourneyaBehavioural Medicine Laboratory, Faculty of Physical Education and Recreation, University of Alberta, Edmonton, Canada.
Cadeyrn J GaskinCentre for Social and Early Emotional Development and School of Psychology, Faculty of Health, Deakin University, Burwood, Australia.
Steve F FraserSchool of Exercise and Nutrition Sciences, Faculty of Health, Deakin University, Burwood, Australia.
Mohammadreza MohebbiFaculty of Health, Deakin University, Burwood, Australia.
Suzanne BroadbentSchool of Health and Human Sciences, Southern Cross University, Lismore, Australia.
Mari BottiSchool of Nursing and Midwifery, Faculty of Health, Deakin University, Burwood, Australia.
Bridie KentSchool of Nursing and Midwifery, Faculty of Health and Human Sciences, University of Plymouth, Plymouth, England.
ENGAGE Uro-Oncology Clinicians' Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to determine the efficacy of a clinician referral and exercise program in improving exercise levels and quality of life for men with prostate cancer.

methodsThis was a multicenter cluster randomized controlled trial in Melbourne, Australia comprising 15 clinicians: 8 clinicians were randomized to refer eligible participants (n = 54) to a 12-week exercise program comprising 2 supervised gym sessions and 1 home-based session per week, and 7 clinicians were randomized to follow usual care (n = 93). The primary outcome was self-reported physical activity; the secondary outcomes were quality of life, anxiety, and symptoms of depression.

resultsA significant intervention effect was observed for vigorous-intensity exercise (effect size: Cohen's d, 0.46; 95% confidence interval [CI], 0.09-0.82; P = .010) but not for combined moderate and vigorous exercise levels (effect size: d, 0.08; 95% CI, -0.28 to 0.45; P = .48). Significant intervention effects were also observed for meeting exercise guidelines (≥150 min/wk; odds ratio, 3.9; 95% CI, 1.9-7.8; P = .002); positive intervention effects were observed in the intervention group for cognitive functioning (effect size: d, 0.34; 95% CI, -0.02 to 0.70; P = .06) and depression symptoms (effect size: d, -0.35; 95% CI, -0.71 to 0.02; P = .06). Eighty percent of participants reported that the clinician's referral influenced their decision to participate in the exercise program.

conclusionsThe clinician referral and 12-week exercise program significantly improved vigorous exercise levels and had a positive impact on mental health outcomes for men living with prostate cancer. Further research is needed to determine the sustainability of the exercise program and its generalizability to other cancer populations.

Indexed as

ExerciseReferral and ConsultationAccelerometryAdultAgedAged, 80 and overAnxietyAustraliaDepressionHumansMaleMiddle AgedMotor ActivityPatient ComplianceProstatic NeoplasmsQuality of Lifeclinician referralexercise programphysical activityprostate cancerquality of life

Identifiers

PMID25877784
PMCPMC4654333

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.