Evidence map›Paper›PMID 25877773›Full record

Trial reportZeitschrift fur Gerontologie und Geriatrie2016

Prevalence and definition of sarcopenia in community dwelling older people. Data from the Berlin aging study II (BASE-II).

D Spira, K Norman, J Nikolov, I Demuth, E Steinhagen-Thiessen, R Eckardt

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Zeitschrift fur Gerontologie und Geriatrie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Prevalence of Sarcopenia Among the Elderly in Korea: A Meta-Analysis.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2021
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Observational
  10. [Musculoskeletal factors, sarcopenia and falls in old age].Zeitschrift fur Gerontologie und Geriatrie · 2019
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. [Sarcopenia and strength].Zeitschrift fur Gerontologie und Geriatrie · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

D SpiraCharité Research Group on Geriatrics, Charité-Universitätsmedizin, Reinickendorfer Str. 61, 13347, Berlin, Germany. dominik.spira@charite.de.
K NormanCharité Research Group on Geriatrics, Charité-Universitätsmedizin, Reinickendorfer Str. 61, 13347, Berlin, Germany.
J NikolovCharité Research Group on Geriatrics, Charité-Universitätsmedizin, Reinickendorfer Str. 61, 13347, Berlin, Germany.
I DemuthCharité Research Group on Geriatrics, Charité-Universitätsmedizin, Reinickendorfer Str. 61, 13347, Berlin, Germany.
E Steinhagen-ThiessenCharité Research Group on Geriatrics, Charité-Universitätsmedizin, Reinickendorfer Str. 61, 13347, Berlin, Germany.
R EckardtCharité Research Group on Geriatrics, Charité-Universitätsmedizin, Reinickendorfer Str. 61, 13347, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia describes the age-associated loss of muscle mass, strength and function. The aim of this study was to compare the prevalence of sarcopenia in a cohort of community dwelling elderly people living in Berlin, Germany, according to the criteria proposed by current consensus statements and to study the respective impact on self-reported physical performance. MATERIAL AND

methodsThis study included 1405 participants from the Berlin aging study II (BASE-II). The appendicular skeletal muscle mass index (SMI) was assessed with dual energy X-ray absorptiometry (DXA), muscle strength was measured by hand grip strength and the timed up and go" test (TUG) was performed as a functional parameter to reflect mobility.

resultsThe prevalence of sarcopenia was 24.3 % in terms of reduced SMI only and considerably lower for sarcopenia with reduced grip strength (4.1 %) and sarcopenia with limited mobility (2.4 %). Only 0.6 % of the participants fulfilled all three criteria. Of the subjects with a normal SMI, 8.6 % had reduced grip strength and 5.1 % had limited mobility, whereas 1.3 % subjects fulfilled both criteria. Participants with reduced strength or function reported severe difficulties in performing physical tasks significantly more often than participants with normal or reduced SMI alone (p <0.029-p <0.0001).

conclusionIn BASE-II low skeletal muscle mass was much more frequent than reduced grip strength or poor function. Reduced strength and function were found to be associated with a greater impact on physical performance than reduced muscle mass. Low SMI does not seem to be a prerequisite for low strength or limitations in mobility.

Indexed as

Absorptiometry, PhotonAgedAged, 80 and overAge DistributionBerlinFemaleGeriatric AssessmentGermanyHand StrengthHumansIndependent LivingMaleMiddle AgedMuscle WeaknessPrevalenceReproducibility of ResultsCommunity dwelling older peopleLimited mobilityMuscle massReduced hand grip strengthSarcopenia

Identifiers

PMID25877773
OpenAlexW1224066628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.