Trial reportInternational orthopaedics2015
Application of pulsed electromagnetic fields after microfractures to the knee: a mid-term study.
Trial report in International orthopaedics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and influencing factors of nonunion in patients with tibial fracture: systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2020Pooled it
- Pulsed electromagnetic fields induce ferroptosis in osteosarcoma cells and promote osteogenic differentiation.Journal of bone oncology · 2026Article
- Pulsed electromagnetic fields after intramedullary nailing of tibial fractures: a case control study.International orthopaedics · 2021Article
- Pulsed Electromagnetic Field Stimulation of Bone Healing and Joint Preservation: Cellular Mechanisms of Skeletal Response.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2020Review
- Pulsed electromagnetic fields promote repair of focal articular cartilage defects with engineered osteochondral constructs.Biotechnology and bioengineering · 2020Article
- Pulsed Electromagnetic Fields and Tissue Engineering of the Joints.Tissue engineering. Part B, Reviews · 2018Article
- Knee cartilage defect: marrow stimulating techniques.Current reviews in musculoskeletal medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePulsed electromagnetic fields (PEMFs) may improve clinical outcomes following microfractures and prevent their decline over time.
methodsSixty-eight patients who underwent partial medial meniscectomy and microfractures to the medial femoral condyle for management of grade III-IV cartilage lesions were randomly divided into two groups using a block randomization procedure. After surgery, 34 patients underwent PEMFs application in the I-ONE group; 34 patients underwent placebo treatment in the placebo group. All patients had the same postoperative rehabilitation protocol. Sixty patients (28 in the I-ONE group, 32 in the placebo group) were assessed at an intermediate follow-up of two years and a minimum follow-up of five years after surgery.
resultsThe two groups were homogeneous. There was a significant improvement from baseline to the last minimum follow up of two years. At two years, IKDC and Lysholm and Constant scores were significantly improved compared to baseline in both groups with no significant inter-group differences. At the last follow up (minimum five years), clinical and functional outcomes were decreased in both the groups, with significant better outcomes in the I-ONE group. At five years, the percentage of patients still active at the same level they were pre-operatively was greater in the I-ONE group (82% vs 68%, P = 0.28). At radiographic assessment, at the latest evaluation, six patients (21.4%) in the I-ONE group and nine (28.1%) in the placebo group demonstrated grade I-II degenerative changes according to Fairbank grading system (Χ = 0.36, P = 0.55).
conclusionsPEMFs application can improve the effectiveness of microfracture in the long term.
Indexed as
Identifiers
25876224What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.