Evidence map›Paper›PMID 25875945›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2015

Gender differences in therapeutic recommendation after diagnostic coronary angiography: insights from the Coronary Angiography and PCI Registry of the German Society of Cardiology.

Tobias Heer, Matthias Hochadel, Karin Schmidt, Julinda Mehilli, Ralf Zahn, Karl-Heinz Kuck, Christian Hamm, Michael Böhm, Georg Ertl, Dietrich Andresen and 5 more

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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Coronary artery disease in women.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2018
    Review
  3. Assessing and Modifying Coronary Artery Disease Risk in Women.Current treatment options in cardiovascular medicine · 2017
    Review
  4. Article
  5. Gender-specific uncertainties in the diagnosis of acute coronary syndrome.Clinical research in cardiology : official journal of the German Cardiac Society · 2017
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Tobias HeerDepartment of Cardiology, Krankenhaus Agatharied, Academic Teaching Hospital, University of Munich, Norbert-Kerkel-Platz, 83607, Hausham, Germany, tobias.heer@khagatharied.de.
Matthias Hochadel
Karin Schmidt
Julinda Mehilli
Ralf Zahn
Karl-Heinz Kuck
Christian Hamm
Michael Böhm
Georg Ertl
Dietrich Andresen
Steffen Massberg
Jochen Senges
Günter Pilz
Anselm K Gitt
Uwe Zeymer
Stiftung Institut für Herzinfarktforschung · DEKlinikum Ludwigshafen · DEKrankenhaus Agatharied · DELudwig-Maximilians-Universität München · DEAsklepios Klinik St. Georg · DEKerckhoff Klinik · DEUniversitätsklinikum des Saarlandes · DEUniversitätsklinikum Würzburg · DEVivantes Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is information suggesting differences and underuse of invasive coronary diagnostic and therapeutic procedures in women compared to men.

methodsData from consecutive patients (pts) which were enrolled in the Coronary Angiography and PCI Registry of the German Society of Cardiology were analyzed. We compared gender-related differences in diagnosis and therapeutic recommendation of pts undergoing coronary angiography (XA) for stable coronary artery disease (CAD), non-ST elevation acute coronary syndromes (NSTE-ACS) and ST elevation myocardial infarction (STEMI).

resultsFrom 2004 until the end of 2009, data of 1,060,542 invasive procedures in 1,014,996 pts were prospectively registered. One-third (34.6%) of them were female. Women less often had significant CAD, irrespective of the indication for XA. In pts with relevant CAD, percutaneous coronary interventions (PCI) were recommended in 87.1% of women versus 89.1% of men with STEMI [age-adjusted OR (aOR) 0.98, 95% CI 0.93-1.04], in 67.1 vs. 66.8% in NSTE-ACS (aOR 1.10, 1.07-1.12), and in 50.3 vs 49.4% in stable CAD (aOR 1.07, 1.05-1.09).

conclusionsIn pts with significant CAD, there was no difference in recommendation for PCI between the genders in stable CAD, whereas in STEMI and NSTE-ACS women were treated even more often with PCI. There were only minor differences in referral for CABG between women and men. Hence, our data provide strong evidence against a gender bias in use of invasive therapeutic procedures once the diagnosis of significant CAD has been confirmed.

Indexed as

Acute Coronary SyndromeAgedCoronary AngiographyCoronary Artery DiseaseFemaleGermanyHealthcare DisparitiesHumansMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionProspective StudiesRegistriesSex Factors

Identifiers

PMID25875945
OpenAlexW2009004078

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.