Evidence map›Paper›PMID 25875781›Full record

ArticleThe British journal of radiology2015

Carotid and vertebral artery stenosis evaluated by contrast-enhanced MR angiography in nasopharyngeal carcinoma patients after radiotherapy: a prospective cohort study.

L Zhou, P Xing, Y Chen, X Xu, J Shen, X Lu

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Study on carotid artery stenosis after radiotherapy for nasopharyngeal carcinoma.Journal of cancer research and clinical oncology · 2024
    Article
  6. Stroke in Asia.Cerebrovascular diseases extra · 2024
    Review
  7. Article
  8. Article
  9. Vertebral artery stenosis predicts cerebrovascular diseases following radiotherapy for nasopharyngeal carcinoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Radiation-induced carotid artery lesions.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2018
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

L Zhou1 Department of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
P Xing
Y Chen
X Xu
J Shen
X Lu
Soochow University · CNSecond Affiliated Hospital of Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the incidence of carotid artery (CA) and vertebral artery (VA) stenosis by contrast-enhanced MR angiography (CE-MRA) in patients with nasopharyngeal carcinoma (NPC) after radiotherapy.

methods72 patients with NPC after radiotherapy more than 3 years ago were recruited as irradiation group to investigate the incidence and degree of CA and VA stenosis by CE-MRA. The results were compared with those of the control group, which comprised 50 newly diagnosed patients with NPC who had not received radiotherapy.

resultsThere was a higher incidence of CA and VA stenosis in the irradiation group than in the control group in terms of patient number as well as vessel involvement. The incidence of significant (>50%) CA and VA stenosis, except for the basilar artery, was also higher in the irradiation group than in the control group. The most commonly detected stenosis in the irradiation group was found in the internal CA (ICA) and VA, followed by the external CA and common CA (CCA). CCA and/or ICA (CCA/ICA) stenosis was present in 67 (93.1%) of 72 patients, with 27 (37.5%) patients having significant CCA/ICA stenosis. The statistical analysis demonstrated that age at receiving CE-MRA scanning and time interval from radiotherapy were the independent predictors of significant CCA/ICA stenosis.

conclusionThe CE-MRA scanning results showed that the incidence of stenosis seems to exist in a wider range of CAs and VAs in the patients with NPC after radiotherapy than in the patients who had not received radiotherapy, and the incidence of significant CCA/ICA stenosis is higher in patients with older age and longer interval from radiotherapy. ADVANCES IN KNOWLEDGE: Radiation-induced CA and VA stenosis exists widely in patients with NPC after radiotherapy, and its prevalence is more common in patients with older age and longer interval from radiotherapy.

Indexed as

AdultAgedAged, 80 and overCarcinomaCarotid StenosisCase-Control StudiesContrast MediaFemaleHumansIncidenceMagnetic Resonance AngiographyMaleMiddle AgedNasopharyngeal CarcinomaNasopharyngeal NeoplasmsVertebrobasilar InsufficiencyContrast Media

Identifiers

PMID25875781
PMCPMC4628462
OpenAlexW2020262603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.