ArticlePloS one2015
Association between poor glycemic control, impaired sleep quality, and increased arterial thickening in type 2 diabetic patients.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 65 citations in OpenAlex.
- Trial
- Association Between Glucocorticoid Exposure and Objective Sleep Architecture in Rheumatoid Arthritis: An Exploratory Pilot EEG Study.Journal of clinical medicine · 2026Article
- Examining the Influence of Glycemic Management During Sleep on Sleep-Related Bruxism: A Pilot Study.Journal of oral rehabilitation · 2026Article
- Sleep Architecture Changes in Diabetes.Journal of clinical medicine · 2024Review
- The relations of circulating agouti-related peptide and leptin with altered sleep architecture in patients with active Cushing's disease: a pilot study.Journal of endocrinological investigation · 2024Article
- Associations of Slow-Wave Sleep With Prevalent and Incident Type 2 Diabetes in the Multi-Ethnic Study of Atherosclerosis.The Journal of clinical endocrinology and metabolism · 2023Article
- The Relationship between Sleep Duration and Metabolic Syndrome Severity Scores in Emerging Adults.Nutrients · 2023Article
- Transdiagnostic association between subjective insomnia and depressive symptoms in major psychiatric disorders.Frontiers in psychiatry · 2023Article
- Carbohydrate and sleep: An evaluation of putative mechanisms.Frontiers in nutrition · 2022Review
- Changes in subjective sleep quality in patients with type 2 diabetes who did not use Sleep agents: a cross-sectional study according to age and clinical background.Diabetology international · 2022Article
- Effect of protein and carbohydrate distribution among meals on quality of life, sleep quality, inflammation, and oxidative stress in patients with type 2 diabetes: A single-blinded randomized controlled trial.Food science & nutrition · 2021Article
- The association of sleep duration and metabolic syndrome in the Bandare-Kong cohort study, a cross-sectional survey (finding from PERSIAN cohort study).Diabetology & metabolic syndrome · 2021Article
- REM sleep latency as an independent risk for cardiovascular events in hemodialysis patients.Physiological reports · 2021Article
- Circadian Patterns of Patients with Type 2 Diabetes and Obstructive Sleep Apnea.Journal of clinical medicine · 2021Article
- Associations of Insomnia With Hypertension and Coronary Artery Disease Among Patients With Type 2 Diabetes Mellitus.Frontiers in cardiovascular medicine · 2021Article
- Effects of sleep quality on non-alcoholic fatty liver disease: a cross-sectional survey.BMJ open · 2020Article
- Relationship between subjective sleep disturbances and glycaemia in Chinese adults with type 2 diabetes: findings from a 1.5-year follow-up study.Scientific reports · 2019Article
- The Interlinked Rising Epidemic of Insufficient Sleep and Diabetes Mellitus.Healthcare (Basel, Switzerland) · 2019Review
- Improvement of glycemic control by treatment for insomnia with suvorexant in type 2 diabetes mellitus.Journal of clinical & translational endocrinology · 2019Article
- Sleep, Autonomic Nervous Function and Atherosclerosis.International journal of molecular sciences · 2019Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePoor sleep quality is an independent predictor of cardiovascular events. However, little is known about the association between glycemic control and objective sleep architecture and its influence on arteriosclerosis in patients with type-2 diabetes mellitus (DM). The present study examined the association of objective sleep architecture with both glycemic control and arteriosclerosis in type-2 DM patients.
designCross-sectional study in vascular laboratory.
methodsThe subjects were 63 type-2 DM inpatients (M/F, 32/31; age, 57.5±13.1) without taking any sleeping promoting drug and chronic kidney disease. We examined objective sleep architecture by single-channel electroencephalography and arteriosclerosis by carotid-artery intima-media thickness (CA-IMT).
resultsHbA1c was associated significantly in a negative manner with REM sleep latency (interval between sleep-onset and the first REM period) (β=-0.280, p=0.033), but not with other measurements of sleep quality. REM sleep latency associated significantly in a positive manner with log delta power (the marker of deep sleep) during that period (β=0.544, p=0.001). In the model including variables univariately correlated with CA-IMT (REM sleep latency, age, DM duration, systolic blood pressure, and HbA1c) as independent variables, REM sleep latency (β=-0.232, p=0.038), but not HbA1c were significantly associated with CA-IMT. When log delta power was included in place of REM sleep latency, log delta power (β=-0.257, p=0.023) emerged as a significant factor associated with CA-IMT.
conclusionsIn type-2 DM patients, poor glycemic control was independently associated with poor quality of sleep as represented by decrease of REM sleep latency which might be responsible for increased CA-IMT, a relevant marker for arterial wall thickening.
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