Evidence map›Paper›PMID 25875471›Full record

SynthesisPloS one2015

Measuring intensity of end of life care: a systematic review.

Xhyljeta Luta, Maud Maessen, Matthias Egger, Andreas E Stuck, David Goodman, Kerri M Clough-Gorr

Abstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Impact of palliative care consultation on neonatal end-of-life care utilization.Journal of perinatology : official journal of the California Perinatal Association · 2026
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  7. Observational
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  12. Obliged to fight? Patient moral processes in the face of poor prognosis cancer.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
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  15. Article
  16. Surgical Treatment Intensity at the End of Life in Patients With Cancer: A Systematic Review.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
    Review
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  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xhyljeta LutaInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Maud MaessenInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Matthias EggerInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Andreas E StuckInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland; University Department of Geriatrics, Inselspital Bern, Bern, Switzerland.
David GoodmanThe Dartmouth Institute of Health Policy & Clinical Practice, Lebanon, NH, United States of America.
Kerri M Clough-GorrInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland; Section of Geriatrics, Boston University Medical Center, Boston, MA, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies have measured the intensity of end of life care. However, no summary of the measures used in the field is currently available.

objectivesTo summarise features, characteristics of use and reported validity of measures used for evaluating intensity of end of life care.

methodsThis was a systematic review according to PRISMA guidelines. We performed a comprehensive literature search in Ovid Medline, Embase, The Cochrane Library of Systematic Reviews and reference lists published between 1990-2014. Two reviewers independently screened titles, abstracts, full texts and extracted data. Studies were eligible if they used a measure of end of life care intensity, defined as all quantifiable measures describing the type and intensity of medical care administered during the last year of life.

resultsA total of 58 of 1590 potentially eligible studies met our inclusion criteria and were included. The most commonly reported measures were hospitalizations (n = 44), intensive care unit admissions (n = 39) and chemotherapy use (n = 27). Studies measured intensity of care in different timeframes ranging from 48 hours to 12 months. The majority of studies were conducted in cancer patients (n = 31). Only 4 studies included information on validation of the measures used. None evaluated construct validity, while 3 studies considered criterion and 1 study reported both content and criterion validity.

conclusionsThis review provides a synthesis to aid in choosing intensity of end of life care measures based on their previous use but simultaneously highlights the crucial need for more validation studies and consensus in the field.

Indexed as

Terminal CareAntineoplastic AgentsDatabases, FactualHospitalizationHumansIntensive Care UnitsNeoplasmsAntineoplastic Agents

Identifiers

PMID25875471
PMCPMC4396980

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.