Evidence map›Paper›PMID 25875302›Full record

ArticleeLife2015

Insights into mammalian biology from the wild house mouse Mus musculus.

Megan Phifer-Rixey, Michael W Nachman

Abstract read
In one paragraph

Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. bioRxiv : the preprint server for biology · 2026
    Article
  8. Modeling versatility as the hallmark of model organisms.History and philosophy of the life sciences · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Right ventricle remodelling: fromJournal of molecular and cellular cardiology plus · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Diversity ofFrontiers in cell and developmental biology · 2025
    Article
  20. Article

49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Megan Phifer-RixeyDepartment of Integrative Biology, University of California, Berkeley, Berkeley, United States and Museum of Vertebrate Zoology, University of California, Berkeley, Berkeley, United States.
Michael W NachmanDepartment of Integrative Biology, University of California, Berkeley, Berkeley, United States and Museum of Vertebrate Zoology, University of California, Berkeley, Berkeley, United States.

Funding

Natural selection and DNA sequence variation in MusR01GM074245 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI NACHMAN, MICHAEL W. · 2005 to 2015
$3.0M
NIGMS NIH HHS R01 GM074245
6 · The paper itself

Abstract

The house mouse, Mus musculus, was established in the early 1900s as one of the first genetic model organisms owing to its short generation time, comparatively large litters, ease of husbandry, and visible phenotypic variants. For these reasons and because they are mammals, house mice are well suited to serve as models for human phenotypes and disease. House mice in the wild consist of at least three distinct subspecies and harbor extensive genetic and phenotypic variation both within and between these subspecies. Wild mice have been used to study a wide range of biological processes, including immunity, cancer, male sterility, adaptive evolution, and non-Mendelian inheritance. Despite the extensive variation that exists among wild mice, classical laboratory strains are derived from a limited set of founders and thus contain only a small subset of this variation. Continued efforts to study wild house mice and to create new inbred strains from wild populations have the potential to strengthen house mice as a model system.

Indexed as

AnimalsGenetic SpeciationGenetic VariationImmunityInheritance PatternsMammalsMicePhenotypePhylogenychromosomesclassical inbred strainevolutionevolutionary biologygenesgenomicshouse mousemouseMus musculusthe natural history of model organismswild mice

Identifiers

PMID25875302
PMCPMC4397906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.