Evidence map›Paper›PMID 25875227›Full record

Trial reportDer Orthopade2015

Experiences with PMMA cement as a stand-alone intervertebral spacer: Percutaneous cement discoplasty in the case of vacuum phenomenon within lumbar intervertebral discs.

P P Varga, G Jakab, I B Bors, A Lazary, Z Szövérfi

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Der Orthopade, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Biomechanical consequences of cement discoplasty: AnFrontiers in bioengineering and biotechnology · 2022
    Article
  17. Article
  18. AnFrontiers in bioengineering and biotechnology · 2022
    Article
  19. Review
  20. Percutaneous cement discoplasty for the treatment of advanced degenerative disk disease in elderly patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

P P VargaNational Center for Spinal Disorders, Kiralyhago u. 1-3, 1126, Budapest, Hungary. vpp@bhc.hu.
G JakabNational Center for Spinal Disorders, Kiralyhago u. 1-3, 1126, Budapest, Hungary.
I B BorsNational Center for Spinal Disorders, Kiralyhago u. 1-3, 1126, Budapest, Hungary.
A LazaryNational Center for Spinal Disorders, Kiralyhago u. 1-3, 1126, Budapest, Hungary.
Z SzövérfiNational Center for Spinal Disorders, Kiralyhago u. 1-3, 1126, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe treatment of symptomatic degenerative disc disease of the lumbar spine in elderly patients by standard surgical methods is often limited due to severe comorbidities (e.g., cardiopulmonary disease, hypertonia, diabetes). Minimally invasive procedures are more acceptable in this population, since they reduce surgical morbidity and the risk of complications. The percutaneous cement discoplasty (PCD) technique was introduced by the authors to treat dynamic (and angular) instability of the symptomatic lumbar segment by injecting bone cement (polymethylmethacrylate, PMMA) into the disc spaces showing vacuum phenomena via a posterolaterally positioned Jamshidi needle. The aim of this article is to describe the indication, method, and clinical results of PCD.

methodA total of 81 patients were treated with PCD in a tertiary care referral center over a 6-year period. The current study includes the first group of 47 consecutive patients to complete a pre- and postoperative questionnaire booklet regarding leg and back pain using the visual analog scale (VAS) and the Oswestry disability index (ODI) questionnaire.

resultsA total of 130 discs in these 47 patients were treated with PCD. The majority of patients reported a reduction in their lower back and leg pain (69% and 66%, respectively; p < 0.02) postoperatively. At 6-month follow-up, 61% of patients had a minimum 10-point reduction in their ODI scores (p < 0.01).

conclusionElderly patients with symptomatic dynamic foraminal stenosis and vacuum phenomenon in the intervertebral disc are suitable candidates for PCD, particularly if they represent high-risk patients for open surgery.

Indexed as

AdultAgedAged, 80 and overBone CementsDiskectomyFemaleHumansIntervertebral Disc DegenerationKyphoplastyLow Back PainMaleMiddle AgedPolymethyl MethacrylateRadiographyTotal Disc ReplacementTreatment OutcomeBone CementsPolymethyl MethacrylateAging spineBone cementChronic painDynamic foraminal stenosisPercutaneous cement discoplasty

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.