Evidence map›Paper›PMID 25875119›Full record

ArticleNutrients2015

A green algae mixture of Scenedesmus and Schroederiella attenuates obesity-linked metabolic syndrome in rats.

Senthil Arun Kumar, Marie Magnusson, Leigh C Ward, Nicholas A Paul, Lindsay Brown

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  4. Article
  5. Article
  6. Metabolomic Evaluation ofNutrients · 2019
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  10. Anti-oxidant and anti-hyperlipidemic activity ofAvicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Senthil Arun KumarCentre for Systems Biology, University of Southern Queensland, Toowoomba 4350, Australia. senthil.ibt@gmail.com.
Marie MagnussonMACRO-the Centre for Macroalgal Resources & Biotechnology, College of Marine and Environmental Sciences, James Cook University, Townsville 4811, Australia. marie.magnusson@jcu.edu.au.
Leigh C WardSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane 4072, Australia. l.ward@uq.edu.au.
Nicholas A PaulMACRO-the Centre for Macroalgal Resources & Biotechnology, College of Marine and Environmental Sciences, James Cook University, Townsville 4811, Australia. nicholas.paul@jcu.edu.au.
Lindsay BrownSchool of Health and Wellbeing, University of Southern Queensland, Toowoomba 4350, Australia. Lindsay.Brown@usq.edu.au.
James Cook University · AUUniversity of Southern Queensland · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the responses to a green algae mixture of Scenedesmus dimorphus and Schroederiella apiculata (SC) containing protein (46.1% of dry algae), insoluble fibre (19.6% of dry algae), minerals (3.7% of dry algae) and omega-3 fatty acids (2.8% of dry algae) as a dietary intervention in a high carbohydrate, high fat diet-induced metabolic syndrome model in four groups of male Wistar rats. Two groups were fed with a corn starch diet containing 68% carbohydrates as polysaccharides, while the other two groups were fed a diet high in simple carbohydrates (fructose and sucrose in food, 25% fructose in drinking water, total 68%) and fats (saturated and trans fats from beef tallow, total 24%). High carbohydrate, high fat-fed rats showed visceral obesity with hypertension, insulin resistance, cardiovascular remodelling, and nonalcoholic fatty liver disease. SC supplementation (5% of food) lowered total body and abdominal fat mass, increased lean mass, and attenuated hypertension, impaired glucose and insulin tolerance, endothelial dysfunction, infiltration of inflammatory cells into heart and liver, fibrosis, increased cardiac stiffness, and nonalcoholic fatty liver disease in the high carbohydrate, high fat diet-fed rats. This study suggests that the insoluble fibre or protein in SC helps reverse diet-induced metabolic syndrome.

Indexed as

ChlorophytaDietary SupplementsScenedesmusAnimalsAnti-Obesity AgentsBlood GlucoseBody CompositionCardiovascular DiseasesCholesterolDietary CarbohydratesDietary FatsDietary FiberDiet, High-FatFatty Acids, Omega-3FructoseGlucose Tolerance TestAnti-Obesity AgentsBlood GlucoseCholesterolDietary CarbohydratesDietary FatsDietary FiberFatty Acids, Omega-3FructoseInsulinMagnesiumPotassium, DietarySodium, DietarySucroseTriglycerides

Identifiers

PMID25875119
PMCPMC4425172
OpenAlexW2160639107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.