Trial reportPloS one2015
Auricular acupressure on specific points for hemodialysis patients with insomnia: a pilot randomized controlled trial.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Auricular Acupressure for Hemodialysis Patients With Insomnia: Study Protocol for a Multi-centre Double-blind, Randomized Controlled Trial
The Effect of Acupuncture for Insomnia in Breast Cancer Patients Undergoing Chemotherapy: A Randomized, Sham-Controlled Trial
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Auricular Acupressure for Insomnia in Patients With Maintenance Hemodialysis: A Systematic Review and Meta-Analysis.Frontiers in psychiatry · 2021Pooled it
- Interventions for improving sleep quality in people with chronic kidney disease.The Cochrane database of systematic reviews · 2019Pooled it
- Acupuncture and related interventions for symptoms of chronic kidney disease.The Cochrane database of systematic reviews · 2016Pooled it
- The Effect of auriculotherapy on sleep quality in children with attention deficit hyperactivity disorder: a randomized clinical trial.BMC pediatrics · 2025Trial
- Acupuncture for chemotherapy-associated insomnia in breast cancer patients: an assessor-participant blinded, randomized, sham-controlled trial.Breast cancer research : BCR · 2023Trial
- Non-Pharmacological Interventions for Sleep Quality and Related Symptoms in Patients with End-Stage Renal Disease: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Efficacy and Safety of Acupuncture Combined with Estazolam for Insomnia in Hemodialysis Patients: A Single-Center, Randomized Controlled Trial.Chinese journal of integrative medicine · 2026Article
- Review
- Acupoint massage: a comprehensive descriptive review of its forms, applications, and underlying mechanisms.Chinese medicine · 2025Review
- Efficacy and safety of auricular acupressure on reduction of estazolam in patients with insomnia: a study protocol for a three-arm, blinded randomized controlled trial.BMC complementary medicine and therapies · 2024Article
- Adaptive Auricular Point Acupressure for Sleep Disturbance in Women with Breast Cancer: A Randomized Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Efficacy of auricular plaster therapy for sleep disorders in preschool children with autism spectrum disorders: Study protocol for a randomized controlled trial.Frontiers in neurology · 2022Article
- Auricular acupressure for insomnia in hemodialysis patients: study protocol for a randomized controlled trial.Trials · 2018Article
- Incidence and severity of nausea and vomiting in a group of maintenance hemodialysis patients.Journal of renal injury prevention · 2017Article
- Electroacupuncture Plus Auricular Acupressure on Chemotherapy-Related Insomnia in Patients With Breast Cancer (EACRI): Study Protocol for a Randomized, Sham-Controlled Trial.Integrative cancer therapiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the feasibility and acceptability of a randomized controlled trial compared auricular acupressure (AA) on specific acupoints with AA on non-specific acupoints for treating maintenance hemodialysis (MHD) patients with insomnia.
methodsSixty three (63) eligible subjects were randomly assigned into either AA group received AA on specific acupoints (n=32), or sham AA (SAA) group received AA on points irrelevant to insomnia treatment (n=31) for eight weeks. All participants were followed up for 12 weeks after treatments. The primary outcome was clinical response at eight weeks after randomization, defined as a reduction of Pittsburgh Sleep Quality Index (PSQI) global score by 3 points and more.
resultsFifty-eight (58) participants completed the trial and five dropped out. Twenty participants in AA group (62.5%) and ten in SAA group (32.3%) responded to the eight-week interventions (χ2 = 5.77, P = 0.02). PSQI global score declined 3.75 ± 4.36 (95%CI -5.32, -2.18) and 2.26 ± 3.89 (95%CI -3.68, -0.83) in AA group and SAA group respectively. Three participants died during the follow-up period. No evidence supported their deaths were related to the AA intervention. No other adverse event was observed.
conclusionFeasibility and logistics of patient recruitment, randomization procedure, blinding approach, interventions application and outcome assessment had been tested in this pilot trial. The preliminary data appeared to show a favorable result on AA treatment. A full-scale trial is warranted.
trial registrationChinese Clinical Trial Registry ChiCTR-TRC-12002272.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.