Evidence map›Paper›PMID 25874640›Full record

ArticlePloS one2015

Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus.

Joon Mo Yang, Christopher Favazza, Junjie Yao, Ruimin Chen, Qifa Zhou, K Kirk Shung, Lihong V Wang

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
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  8. Article
  9. Review
  10. Article
  11. 3D acoustic resolution-based photoacoustic endoscopy with dynamic focusing.Quantitative imaging in medicine and surgery · 2021
    Article
  12. Article
  13. Ultra-Compact Microsystems-Based Confocal Endomicroscope.IEEE transactions on medical imaging · 2020
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Optoacoustic mesoscopy for biomedicine.Nature biomedical engineering · 2019
    Review
  19. Functional endoscopy techniques for tracking stem cell fate.Quantitative imaging in medicine and surgery · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Joon Mo YangOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri, United States of America.
Christopher FavazzaOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri, United States of America.
Junjie YaoOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri, United States of America.
Ruimin ChenNational Institutes of Health Ultrasonic Transducer Resource Center, Department of Biomedical Engineering, University of Southern California, Los Angeles, California, United States of America.
Qifa ZhouNational Institutes of Health Ultrasonic Transducer Resource Center, Department of Biomedical Engineering, University of Southern California, Los Angeles, California, United States of America.
K Kirk ShungNational Institutes of Health Ultrasonic Transducer Resource Center, Department of Biomedical Engineering, University of Southern California, Los Angeles, California, United States of America.
Lihong V WangOptical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, Missouri, United States of America.
National Institutes of Health · USOptica · USWashington University in St. Louis · US

Funding

PHOTON TUNNELING: SHEDDING NEW LIGHT ON BIOMEDICINEDP1EB016986 · NIBIB · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2012 to 2016
$3.8M
IN VIVO IMAGING OF SINGLE CIRCULATING CELLSR01CA186567 · NCI · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2013 to 2017
$3.6M
PHOTOACOUSTIC MICROSCOPY OF NEOVASCULARIZATION IN RENAL CANCER GROWTH AND THERAPYR01CA159959 · NCI · WASHINGTON UNIVERSITY · PI ARBEIT, JEFFREY MICHAEL · 2011 to 2015
$2.9M
Photoacoustic endoscopy of Barretts esophagusR01CA157277 · NCI · WASHINGTON UNIVERSITY · PI MEYERS, BRYAN F, ZHOU, QIFA · 2010 to 2014
$2.7M
NCI NIH HHS R01 CA157277NCI NIH HHS R01 CA159959NCI NIH HHS R01 CA186567NIBIB NIH HHS DP1 EB016986NIBIB NIH HHS EB016986
6 · The paper itself

Abstract

We report photoacoustic and ultrasonic endoscopic images of two intact rabbit esophagi. To investigate the esophageal lumen structure and microvasculature, we performed in vivo and ex vivo imaging studies using a 3.8-mm diameter photoacoustic endoscope and correlated the images with histology. Several interesting anatomic structures were newly found in both the in vivo and ex vivo images, which demonstrates the potential clinical utility of this endoscopic imaging modality. In the ex vivo imaging experiment, we acquired high-resolution motion-artifact-free three-dimensional photoacoustic images of the vasculatures distributed in the walls of the esophagi and extending to the neighboring mediastinal regions. Blood vessels with apparent diameters as small as 190 μm were resolved. Moreover, by taking advantage of the dual-mode high-resolution photoacoustic and ultrasound endoscopy, we could better identify and characterize the anatomic structures of the esophageal lumen, such as the mucosal and submucosal layers in the esophageal wall, and an esophageal branch of the thoracic aorta. In this paper, we present the first photoacoustic images showing the vasculature of a vertebrate esophagus and discuss the potential clinical applications and future development of photoacoustic endoscopy.

Indexed as

AnimalsEndosonographyEsophagusImaging, Three-DimensionalPhotoacoustic TechniquesRabbits

Identifiers

PMID25874640
PMCPMC4398324
OpenAlexW2010917511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.