ArticlePloS one2015
Cell type-specific separation of subicular principal neurons during network activities.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Evidence of spatial periodic firing in the subiculum of mice.Frontiers in neural circuits · 2025Article
- Coupling of Sharp Wave Events between Zebrafish Hippocampal and Amygdala Homologs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Cell-specific switch for epileptiform activity: critical role of interneurons in the mouse subicular network.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Exposure to Short Photoperiod Regime Restores Spatial Cognition in Ventral Subicular Lesioned Rats: Potential Role of Hippocampal Plasticity, Glucocorticoid Receptors, and Neurogenesis.Molecular neurobiology · 2021Article
- Subiculum as a generator of sharp wave-ripples in the rodent hippocampus.Cell reports · 2021Article
- Synaptic organisation and behaviour-dependent activity of mGluR8a-innervated GABAergic trilaminar cells projecting from the hippocampus to the subiculum.Brain structure & function · 2020Article
- Heterogeneity within classical cell types is the rule: lessons from hippocampal pyramidal neurons.Nature reviews. Neuroscience · 2019Review
- In vitro characterization of gamma oscillations in the hippocampal formation of the domestic chick.The European journal of neuroscience · 2018Article
- The role of T-type calcium channels in the subiculum: to burst or not to burst?The Journal of physiology · 2017Article
- Functional Diversity of Subicular Principal Cells during Hippocampal Ripples.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Neural Activity Patterns Underlying Spatial Coding in the Hippocampus.Current topics in behavioral neurosciencesReview
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Authors and funding
5 authors.
Funding
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Abstract
The hippocampal output structure, the subiculum, expresses two major memory relevant network rhythms, sharp wave ripple and gamma frequency oscillations. To this date, it remains unclear how the two distinct types of subicular principal cells, intrinsically bursting and regular spiking neurons, participate in these two network rhythms. Using concomitant local field potential and intracellular recordings in an in vitro mouse model that allows the investigation of both network rhythms, we found a cell type-specific segregation of principal neurons into participating intrinsically bursting and non-participating regular spiking cells. However, if regular spiking cells were kept at a more depolarized level, they did participate in a specific manner, suggesting a potential bimodal working model dependent on the level of excitation. Furthermore, intrinsically bursting and regular spiking cells exhibited divergent intrinsic membrane and synaptic properties in the active network. Thus, our results suggest a cell-type-specific segregation of principal cells into two separate groups during network activities, supporting the idea of two parallel streams of information processing within the subiculum.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.