Evidence map›Paper›PMID 25874381›Full record

ArticlePloS one2015

Has Madagascar lost its exceptional leptospirosis free-like status?

Maherisoa Ratsitorahina, Soanandrasana Rahelinirina, Alain Michault, Minoarisoa Rajerison, Soatiana Rajatonirina, Vincent Richard, 2011 Surveillance Workshop group

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Applied and environmental microbiology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Parasitology · 2019
    Article
  7. Seroprevalence ofInternational journal of environmental research and public health · 2019
    Article
  8. High Prevalence ofThe American journal of tropical medicine and hygiene · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maherisoa RatsitorahinaEpidemiology Unit, Pasteur Institute of Madagascar, BP 1274, Antananarivo, Madagascar.
Soanandrasana RahelinirinaPlague Unit, Pasteur Institute of Madagascar, BP 1274, Antananarivo, Madagascar.
Alain MichaultBiology, Virology and Parasitology Units, Centre Hospitalier Universitaire (CHU Sud), St. Pierre, Reunion Island, France.
Minoarisoa RajerisonPlague Unit, Pasteur Institute of Madagascar, BP 1274, Antananarivo, Madagascar.
Soatiana RajatonirinaEpidemiology Unit, Pasteur Institute of Madagascar, BP 1274, Antananarivo, Madagascar.
Vincent RichardEpidemiology Unit, Pasteur Institute of Madagascar, BP 1274, Antananarivo, Madagascar; Epidemiology Unit, Pasteur Institute of Dakar, BP 220, Dakar, Senegal.
2011 Surveillance Workshop group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeptospirosis is a widespread but underreported cause of morbidity and mortality. It has rarely been reported in either humans or animals in Madagascar.

methodsWe conducted a cross-sectional survey of the inhabitants in Moramanga, Madagascar, in June 2011, to estimate the prevalence of human infection using the microscopic agglutination test (MAT). This activity was carried out as part of a workshop implemented by the Pasteur Institute of Madagascar, focusing on surveillance with a one week field study and targeting the health staff of the district level.

resultsIn total, we sampled 678 inhabitants from 263 households. The sex ratio (M/F) was 0.65 and the mean age 26.7 years. We obtained a value of 2.9% for the first recorded seroprevalence of this disease in the human community of Moramanga. Questionnaire responses revealed frequent contacts between humans and rodents in Moramanga. However, activities involving cattle were identified as a risk factor significantly associated with seropositivity (OR=3).

conclusionLeptospirosis remains a neglected disease in Madagascar. This study highlights the need to quantify the public health impact of this neglected disease in a more large scale, in all the country and to establish point-of-care laboratories in remote areas.

Indexed as

AdolescentAdultAgedAged, 80 and overAgglutination TestsAnimalsAnimals, DomesticAntibodies, BacterialCattleCattle DiseasesChildChild, PreschoolCross-Sectional StudiesDisease ReservoirsFemaleHousingAntibodies, Bacterial

Identifiers

PMID25874381
PMCPMC4396993

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.