Evidence map›Paper›PMID 25874234›Full record

ArticleBioMed research international2015

Identification of novel thyroid cancer-related genes and chemicals using shortest path algorithm.

Yang Jiang, Peiwei Zhang, Li-Peng Li, Yi-Chun He, Ru-jian Gao, Yu-Fei Gao

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yang JiangDepartment of Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.ORCID 0000-0002-1901-9778
Peiwei ZhangThe Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Li-Peng LiDepartment of Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
Yi-Chun HeDepartment of Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
Ru-jian GaoDepartment of Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
Yu-Fei GaoDepartment of Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
Union Hospital · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer is a typical endocrine malignancy. In the past three decades, the continued growth of its incidence has made it urgent to design effective treatments to treat this disease. To this end, it is necessary to uncover the mechanism underlying this disease. Identification of thyroid cancer-related genes and chemicals is helpful to understand the mechanism of thyroid cancer. In this study, we generalized some previous methods to discover both disease genes and chemicals. The method was based on shortest path algorithm and applied to discover novel thyroid cancer-related genes and chemicals. The analysis of the final obtained genes and chemicals suggests that some of them are crucial to the formation and development of thyroid cancer. It is indicated that the proposed method is effective for the discovery of novel disease genes and chemicals.

Indexed as

Databases, GeneticLigandsAlgorithmsDrug DiscoveryHumansProtein Interaction MapsSignal TransductionThyroid GlandThyroid NeoplasmsLigands

Identifiers

PMID25874234
PMCPMC4385622
OpenAlexW2078932621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.