ArticleCase reports in emergency medicine2015
An Atypical Case of Methemoglobinemia due to Self-Administered Benzocaine.
Article in Case reports in emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- Methemoglobinemia in Infancy.Annals of African medicine · 2026Article
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- Methylene blue-induced Hemolysis in a patient with lidocaine-induced Methemoglobinemia: a case report.Oxford medical case reports · 2025Article
- A case report on acute combined poisoning of Indoxacarb and Novoluron and its management.SAGE open medical case reports · 2025Article
- Deadly shades of green: A cautionary tale of an organic biopesticide poisoning.Toxicology reports · 2024Article
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- Methaemoglobinaemia Associated With Mixed Cocaine and Amphetamine Overdose: A Case Report.Cureus · 2024Article
- Diagnosis on sight: Chocolate blood.Journal of the American College of Emergency Physicians open · 2023Article
- Hemolysis and acquired methemoglobinemia associated with lidocaine and benzocaine topical application: a case report.Journal of medical case reports · 2023Article
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- Diagnosis and management of nitrobenzene poisoning in a low-resource setting: A case report.Annals of medicine and surgery (2012) · 2022Article
- Oral Chronic Graft-Versus-Host Disease.Frontiers in oral health · 2022Review
- A Case Report of Acute Transient Encephalopathy Following a Trans-esophageal Echocardiography.Cureus · 2021Article
- Methaemoglobinaemia from Vagisil creme in a 50-year-old woman.BMJ case reports · 2021Article
- Anemia That Presented with Desaturation: A Focus on Core Concepts.Case reports in pediatrics · 2021Article
- Mothers' false beliefs and myths associated with teething.Qatar medical journal · 2020Article
- Parkinsonism and Vitamin C Deficiency.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acquired methemoglobinemia is an uncommon hemoglobinopathy that results from exposure to oxidizing agents, such as chemicals or medications. Although, as reported in the adult population, it happens most often due to prescribed medication or procedural anesthesia and not due to easily accessed over-the-counter medications, the authors will describe an otherwise healthy male adult with no known medical history and no prescribed medications, who presented to the emergency department reporting generalized weakness, shortness of breath, headache, dizziness, and pale gray skin. In addition, the patient reported that he also had a severe toothache for several days, which he had been self-treating with an over-the-counter oral benzocaine gel. Ultimately, the diagnosis of methemoglobinemia was made by clinical history, physical examination, and the appearance of chocolate-colored blood and arterial blood gas (ABG) with cooximetry. After 2 mg/kg of intravenous methylene blue was administered, the patient had complete resolution of all signs and symptoms. This case illustrates that emergency physicians should be keenly aware of the potential of toxic hemoglobinopathy secondary to over-the-counter, nonprescribed medications. Discussion with patients regarding the dangers of inappropriate use of these medicines is imperative, as such warnings are typically not evident on product labels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.