ArticleOxidative medicine and cellular longevity2015
Exercise training and calorie restriction influence the metabolic parameters in ovariectomized female rats.
Article in Oxidative medicine and cellular longevity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 43 citations in OpenAlex.
- Comparison of HIIT and MICT and further detraining on metabolic syndrome and asprosin signaling pathway in metabolic syndrome model of rats.Scientific reports · 2024Article
- Effect of calorie restriction on redox status during chemically induced estropause in female mice.GeroScience · 2024Article
- RETRACTED: Protective effects of calorie restriction and 17-β estradiol on cardiac hypertrophy in ovariectomized obese rats.PloS one · 2023Article
- The effects of exercise training induced calories expenditure on type 2 diabetes related cardio metabolic physiological parameters and adipocytokines.Journal of diabetes and metabolic disorders · 2022Article
- Prophylactic effect ofJournal of traditional and complementary medicine · 2022Article
- The Effects of Whole-Body Vibration Exercise Combined With an Isocaloric High-Fructose Diet on Osteoporosis and Immunomodulation in Ovariectomized Mice.Frontiers in nutrition · 2022Article
- Ginkgo biloba extract (GbE) attenuates obesity and anxious/depressive-like behaviours induced by ovariectomy.Scientific reports · 2021Article
- Multiple Applications of Different Exercise Modalities with Rodents.Oxidative medicine and cellular longevity · 2021Review
- Lifestyle-Induced Redox-Sensitive Alterations: Cross-Talk among the RAAS, Antioxidant/Inflammatory Status, and Hypertension.Oxidative medicine and cellular longevity · 2021Article
- Ovariectomized rodents as a menopausal metabolic syndrome model. A minireview.Molecular and cellular biochemistry · 2020Review
- Comparative analysis of the influence of a high-fat/high-carbohydrate diet on the level of anxiety and neuromotor and cognitive functions in Wistar and DAT-KO rats.Physiological reports · 2019Article
- Postconditioning-like effect of exercis: new paradigm in experimental menopause.American journal of physiology. Heart and circulatory physiology · 2019Article
- The Effects of Exercise Training and High Triglyceride Diet in an Estrogen Depleted Rat Model: The Role of the Heme Oxygenase System and Inflammatory Processes in Cardiovascular Risk.Journal of sports science & medicine · 2018Article
- Article
- Role of Exercise-Induced Cardiac Remodeling in Ovariectomized Female Rats.Oxidative medicine and cellular longevity · 2018Article
- Modified lingguizhugan decoction incorporated with dietary restriction and exercise ameliorates hyperglycemia, hyperlipidemia and hypertension in a rat model of the metabolic syndrome.BMC complementary and alternative medicine · 2017Article
- Traditional medicine, Sobokchukeo‑Tang, modulates the inflammatory response in adipocytes and macrophages.Molecular medicine reports · 2017Article
- Anti-Atherogenic Properties of Allium ursinum Liophylisate: Impact on Lipoprotein Homeostasis and Cardiac Biomarkers in Hypercholesterolemic Rabbits.International journal of molecular sciences · 2016Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The estrogen deficiency after menopause leads to overweight or obesity, and physical exercise is one of the important modulators of this body weight gain. Female Wistar rats underwent ovariectomy surgery (OVX) or sham operation (SO). OVX and SO groups were randomized into new groups based on the voluntary physical activity (with or without running) and the type of diet for 12 weeks. Rats were fed standard chow (CTRL), high triglyceride diet (HT), or restricted diet (CR). The metabolic syndrome was assessed by measuring the body weight gain, the glucose sensitivity, and the levels of insulin, triglyceride, leptin, and aspartate aminotransferase transaminase (AST) and alanine aminotransferase (ALT). The exercise training combined with the CR resulted in improvements in the glucose tolerance and the insulin sensitivity. Plasma TG, AST, and ALT levels were significantly higher in OVX rats fed with HT but these high values were suppressed by exercise and CR. Compared to SO animals, estrogen deprivation with HT caused a significant increase in leptin level. Our data provide evidence that CR combined with voluntary physical exercise can be a very effective strategy to prevent the development of a metabolic syndrome induced by high calorie diet.
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