Evidence map›Paper›PMID 25874019›Full record

ArticleOxidative medicine and cellular longevity2015

Assessment of eccentric exercise-induced oxidative stress using oxidation-reduction potential markers.

Dimitrios Stagos, Nikolaos Goutzourelas, Amalia-Maria Ntontou, Ioannis Kafantaris, Chariklia K Deli, Athanasios Poulios, Athanasios Z Jamurtas, David Bar-Or, Dimitrios Kouretas

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

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  5. Cytokine profiling in pulmonary arterial hypertension: the role of redox homeostasis and sex.Translational research : the journal of laboratory and clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Dimitrios StagosDepartment of Biochemistry and Biotechnology, University of Thessaly, Ploutonos 26 & Aiolou, 41221 Larissa, Greece.
Nikolaos GoutzourelasDepartment of Biochemistry and Biotechnology, University of Thessaly, Ploutonos 26 & Aiolou, 41221 Larissa, Greece.
Amalia-Maria NtontouDepartment of Biochemistry and Biotechnology, University of Thessaly, Ploutonos 26 & Aiolou, 41221 Larissa, Greece.
Ioannis KafantarisDepartment of Biochemistry and Biotechnology, University of Thessaly, Ploutonos 26 & Aiolou, 41221 Larissa, Greece.
Chariklia K DeliDepartment of Exercise and Sport Sciences, University of Thessaly, 42100 Trikala, Greece.
Athanasios PouliosDepartment of Exercise and Sport Sciences, University of Thessaly, 42100 Trikala, Greece.
Athanasios Z JamurtasDepartment of Exercise and Sport Sciences, University of Thessaly, 42100 Trikala, Greece.
David Bar-OrTrauma Research Department, St. Anthony Hospital, Lakewood, CO 80228, USA ; Trauma Research Department, Swedish Medical Center, Englewood, CO 80113, USA ; Trauma Research Department, Medical Center of Plano, Plano, TX 75075, USA.
Dimitrios KouretasDepartment of Biochemistry and Biotechnology, University of Thessaly, Ploutonos 26 & Aiolou, 41221 Larissa, Greece.
University of Thessaly · GRSt. Anthony Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to investigate the use of static (sORP) and capacity ORP (cORP) oxidation-reduction potential markers as measured by the RedoxSYS Diagnostic System in plasma, for assessing eccentric exercise-induced oxidative stress. Nineteen volunteers performed eccentric exercise with the knee extensors. Blood was collected before, immediately after exercise, and 24, 48, and 72 h after exercise. Moreover, common redox biomarkers were measured, which were protein carbonyls, thiobarbituric acid-reactive substances, total antioxidant capacity in plasma, and catalase activity and glutathione levels in erythrocytes. When the participants were examined as one group, there were not significant differences in any marker after exercise. However, in 11 participants there was a high increase in cORP after exercise, while in 8 participants there was a high decrease. Thus, the participants were divided in low cORP group exhibiting significant decrease in cORP after exercise and in high cORP group exhibiting significant increase. Moreover, only in the low cORP group there was a significant increase in lipid peroxidation after exercise suggesting induction of oxidative stress. The results suggested that high decreases in cORP values after exercise may indicate induction of oxidative stress by eccentric exercise, while high increases in cORP values after exercise may indicate no existence of oxidative stress.

Indexed as

ExerciseOxidative StressAdultAntioxidantsBiomarkersCatalaseErythrocytesFemaleGlutathioneHumansMaleOxidation-ReductionProtein CarbonylationYoung AdultAntioxidantsBiomarkersCatalaseGlutathione

Identifiers

PMID25874019
PMCPMC4385679
OpenAlexW1996973637

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.