ArticleFrontiers in plant science2015
Transcriptome-based gene profiling provides novel insights into the characteristics of radish root response to Cr stress with next-generation sequencing.
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Progress and Impacts of "Omics" Technologies in Understanding the Drought Response in Cassava: Adoption for Food Security in Africa.Plant-environment interactions (Hoboken, N.J.) · 2025Review
- Transcriptome analysis revealed key genes and pathways related to cadmium tolerance and accumulation in coix (Frontiers in plant science · 2025Article
- Combined effects of biochar and biodegradable mulch film on chromium bioavailability and the agronomic characteristics of tobacco.Scientific reports · 2024Article
- Systematic analysis of Heat Shock Protein 70 (HSP70) gene family in radish and potential roles in stress tolerance.BMC plant biology · 2024Article
- Differential RNA-Seq Analysis Predicts Genes Related to Terpene Tailoring inPlants (Basel, Switzerland) · 2023Article
- Systems biology of chromium-plant interaction: insights from omics approaches.Frontiers in plant science · 2023Review
- Genome-wide identification of sugar transporter gene family in Brassicaceae crops and an expression analysis in the radish.BMC plant biology · 2022Article
- Genome-wide analysis of metallothionein gene family in maize to reveal its role in development and stress resistance to heavy metal.Biological research · 2022Article
- Genome-Wide Characterization of the Aquaporin Gene Family in Radish and Functional Analysis ofFrontiers in plant science · 2022Article
- Metabolites produced by inoculated Vigna radiata during bacterial assisted phytoremediation of Pb, Ni and Cr polluted soil.PloS one · 2022Article
- Main Molecular Pathways Associated with Copper Tolerance Response inPlants (Basel, Switzerland) · 2021Article
- In-site and Ex-site Date Palm Exposure to Heavy Metals Involved Infra-Individual Biomarkers Upregulation.Plants (Basel, Switzerland) · 2021Article
- Genome-Wide Identification and Functional Characterization of the Cation Proton Antiporter (CPA) Family Related to Salt Stress Response in Radish (International journal of molecular sciences · 2020Article
- Gene Regulatory Network Guided Investigations and Engineering of Storage Root Development in Root Crops.Frontiers in plant science · 2020Review
- Genome- and Transcriptome-Wide Characterization ofInternational journal of molecular sciences · 2019Article
- Article
- The radish genome database (RadishGD): an integrated information resource for radish genomics.Database : the journal of biological databases and curation · 2019Article
- Root Hair Single Cell Type Specific Profiles of Gene Expression and Alternative Polyadenylation Under Cadmium Stress.Frontiers in plant science · 2019Article
- Response of Tradescantia plants to oxidative stress induced by heavy metal pollution of soils from industrial areas.Environmental science and pollution research international · 2019Article
- Genome-wide transcriptional analysis of submerged lotus reveals cooperative regulation and gene responses.Scientific reports · 2018Article
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Authors and funding
11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Radish (Raphanus sativus L.) is an important worldwide root vegetable crop with high nutrient values and is adversely affected by non-essential heavy metals including chromium (Cr). Little is known about the molecular mechanism underlying Cr stress response in radish. In this study, RNA-Seq technique was employed to identify differentially expressed genes (DEGs) under Cr stress. Based on de novo transcriptome assembly, there were 30,676 unigenes representing 60,881 transcripts isolated from radish root under Cr stress. Differential gene analysis revealed that 2985 uingenes were significantly differentially expressed between Cr-free (CK) and Cr-treated (Cr600) libraries, among which 1424 were up-regulated and 1561 down-regulated. Gene ontology (GO) analysis revealed that these DEGs were mainly involved in primary metabolic process, response to abiotic stimulus, cellular metabolic process and small molecule metabolic process. Kyoto encyclopedia of genes and genomes (KEGG) enrichment analysis showed that the DEGs were mainly involved in protein processing in endoplasmic reticulum, starch and sucrose metabolism, amino acid metabolism, glutathione metabolism, drug and xenobiotics by cytochrome P450 metabolism. RT-qPCR analysis showed that the expression patterns of 12 randomly selected DEGs were highly accordant with the results from RNA-seq. Furthermore, many candidate genes including signaling protein kinases, transcription factors and metal transporters, chelate compound biosynthesis and antioxidant system, were involved in defense and detoxification mechanisms of Cr stress response regulatory networks. These results would provide novel insight into molecular mechanism underlying plant responsiveness to Cr stress and facilitate further genetic manipulation on Cr uptake and accumulation in radish.
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