ArticleDisease markers2015
Circulating soluble neuropilin-1 in patients with early cervical cancer and cervical intraepithelial neoplasia can be used as a valuable diagnostic biomarker.
Article in Disease markers, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Routine Blood-Based Parameters Associated with Invasive Cervical Cancer Versus High-Grade Cervical Intraepithelial Neoplasia: Development of a Retrospective Diagnostic Prediction Model.Diagnostics (Basel, Switzerland) · 2026Article
- Investigating the potential mechanism of quercetin against cervical cancer.Discover oncology · 2023Article
- Circulating Neurovascular Guidance Molecules and Their Relationship with Peripheral Microvascular Impairment in Systemic Sclerosis.Life (Basel, Switzerland) · 2022Article
- Soluble Neuropilin-1 is an independent marker of poor prognosis in early breast cancer.Journal of cancer research and clinical oncology · 2021Article
- The role of Neuropilin-1 in COVID-19.PLoS pathogens · 2021Review
- Diagnostic Value of Circulating PIGF in Combination with Flt-1 in Early Cervical Cancer.Current medical science · 2020Article
- Serum and tissue expression of neuropilin 1 in precancerous and malignant vocal fold lesions.PloS one · 2020Article
- Neuropilin-1 is associated with the prognosis of cervical cancer in Henan Chinese population.OncoTargets and therapy · 2019Article
- Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function.Oncotarget · 2016Article
- Neuropilin Functions as an Essential Cell Surface Receptor.The Journal of biological chemistry · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate soluble neuropilin-1 (sNRP-1) in circulating and NRP-1 protein in cervical tissues from patients with cervical cancer or cervical intraepithelial neoplasia (CIN).
methodssNRP-1 was measured in 64 preoperative patients and 20 controls. NRP-1 protein in cervical tissue was detected in 56 patients and 20 controls.
resultsBoth sNRP-1 and NRP-1 proteins were correlated with stage. sNRP-1 presented a high diagnostic ability of cervical cancer and CIN, with a sensitivity of 70.97% and a specificity of 73.68%.
conclusionssNRP-1 in circulating can serve as a possible valuable diagnostic biomarker for cervical cancer and CIN.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.