Evidence map›Paper›PMID 25873334›Full record

Trial reportTrials2015

The effectiveness of Tai Chi for patients with Parkinson's disease: study protocol for a randomized controlled trial.

Yan Yang, Yan-lei Hao, Wen-jing Tian, Li Gong, Kui Zhang, Qi-guang Shi, Da-fang Sun, Cui-lan Li, Zhi-ling Zhao

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Health benefits of tai chi: What is the evidence?Canadian family physician Medecin de famille canadien · 2016
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Canadian family physician Medecin de famille canadien · 2016
    Review
  9. Effect of Tai Chi Exercise Combined with Mental Imagery Theory in Improving Balance in a Diabetic and Elderly Population.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yan YangDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. yanyangdr@126.com.
Yan-lei HaoDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. yanleihaodr@163.com.
Wen-jing TianDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. wenlingtiandr@163.com.
Li GongDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. ligongdr@126.com.
Kui ZhangDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. kuizhangdr@163.com.
Qi-guang ShiDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. qiguangshidr@163.com.
Da-fang SunDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. dafangsundr@163.com.
Cui-lan LiDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. cuilanlidr@163.com.
Zhi-ling ZhaoDepartment of Neurology, Affiliated Hospital of Jining Medical University, 79 Guhuai Rd, Jining, Shandong, China. zhilingzhaodr@163.com.
Affiliated Hospital of Jining Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParkinson's disease (PD) is a common degenerative neurological disorder that causes loss of independence and decreased quality of life. The prevalence of PD tends to increase with age. In China, the morbidity rate of PD among people aged more than 65 years old is 1.70%. As an important component of traditional Chinese Qigong exercises, Tai Chi is a popular and safe exercise, especially for older adults in China. And it may result in promising gains for PD patients. However, current evidence is insufficient to inform the use of Tai Chi in the management of PD. Therefore, the aim of this trial is to systematically evaluate the effect of Tai Chi on PD and determine whether Tai Chi is an eligible exercise program for Chinese PD patients. METHODS/

designA single-blind, parallel randomized controlled trial will be conducted. One hundred and forty-two patients with PD will be randomly assigned to a Tai Chi group (n = 71) or routine exercise group (n = 71). Subjects will participate in supervised study programs 3 times per week for 2 months and will be followed for an additional 6 months after formal training stops. The primary outcome measures include Berg Balance Scale, Timed Up and Go Test and Six-Minute Walk Test, which are known to be valid and reliable clinical instruments. The Unified Parkinson's Disease Rating Scale Motor Section and Parkinson's Disease Questionnaire-39 will be used as the secondary outcome measure. All outcomes will be measured at baseline, 2 and 8 months. The sample for this trial (N = 142) will provide relevant information to detect the improvement of balance, gait and quality of life in either of the 2 exercise groups. DISCUSSION: Findings from this study will provide insights into the effects of Tai Chi in people with PD. The information gained from this project has the potential to influence the clinical decisions of Chinese doctors, and will provide clear evidence as to whether Tai Chi should be advocated in people with PD.

trial registrationThe trial was registered at ( ChiCTR-TRC-14004549 ) on 22 April 2014.

Indexed as

Tai JiBiomechanical PhenomenaChinaClinical ProtocolsExercise TestExercise ToleranceGaitHumansMotor ActivityParkinson DiseasePostural BalanceQuality of LifeRecovery of FunctionResearch DesignSingle-Blind MethodSurveys and Questionnaires

Identifiers

PMID25873334
PMCPMC4377011
OpenAlexW2044373298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.