Trial reportPediatric pulmonology2015
Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings.
Trial report in Pediatric pulmonology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Lengthening sleep reduces pain in childhood arthritis: a crossover randomised controlled trial.RMD open · 2023Trial
- Impact of sleep opportunity on asthma outcomes in adolescents.Sleep medicine · 2020Trial
- The effects of experimental sleep disruption on daytime performance among children with asthma living in urban environments.Sleep health · 2025Article
- Association between sleep duration and lung function among U.S. adults.BMC public health · 2024Article
- Sleep and allergic diseases among young Chinese adults from the Singapore/Malaysia Cross-Sectional Genetic Epidemiology Study (SMCGES) cohort.Journal of physiological anthropology · 2024Article
- Sleep disorders in children with asthma.Pediatric pulmonology · 2022Review
- Exploring genetic association of insomnia with allergic disease and asthma: a bidirectional Mendelian randomization study.Respiratory research · 2022Article
- The Effect of Short Sleep Duration on the Development of Asthma.International journal of clinical practice · 2022Review
- Experimental methods to study sleep disruption and immune balance in urban children with asthma.Sleep advances : a journal of the Sleep Research Society · 2022Article
- Energy-drink consumption is associated with asthma, allergic rhinitis, and atopic dermatitis in Korean adolescents.European journal of clinical nutrition · 2021Article
- Why Lungs Keep Time: Circadian Rhythms and Lung Immunity.Annual review of physiology · 2020Review
- Feasibility of a Single-Subject Protocol to Shift Young Children's Sleep Schedules.Journal of clinical psychology in medical settings · 2019Article
- Health risk behaviors, violence exposure, and current asthma among adolescents in the United States.Pediatric pulmonology · 2019Article
- Sleep in young children with asthma and their parents.Journal of child health care : for professionals working with children in the hospital and community · 2017Article
- Asthma-related lung function, sleep quality, and sleep duration in urban children.Sleep health · 2017Article
- Serum and Brain Metabolomic Variations Reveal Perturbation of Sleep Deprivation on Rats and Ameliorate Effect of Total Ginsenoside Treatment.International journal of genomics · 2017Article
- Sleep Problems as Consequence, Contributor, and Comorbidity: Introduction to the Special Issue on Sleep, Published in Coordination With Special Issues in Clinical Practice in Pediatric Psychology and Journal of Developmental and Behavioral Pediatrics.Journal of pediatric psychology · 2016Article
- The Development of a Clinically Relevant Sleep Modification Protocol for Youth with Type 1 Diabetes.Clinical practice in pediatric psychology · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo examine the impact of sleep duration on lung function and asthma symptoms in adolescents.
methodsTen adolescents with asthma (60% female, 60% Caucasian, mean age = 13.7 years, range 12-17) completed a 3-week randomized, cross-over sleep manipulation protocol. Following a week of self-selected sleep duration, adolescents were randomized to a five-night deficient sleep opportunity (6.5 hr in bed) or a healthy sleep opportunity (10 hr in bed) obtained by systematically changing bedtimes. Wake time remained consistent across all 3 weeks (including weekends). Daily reports of sleep patterns and asthma symptoms, actigraphy, and daily peak expiratory flow rates (PEFR), as well as weekly spirometry and exhaled nitric oxide were collected.
resultsParticipants averaged 3.2 hr less sleep (P < 0.001) per night in the short sleep condition versus the long sleep condition. Further, they had an 8.4% decrease overnight in PEFR (P = 0.007), and reported more asthma symptoms interfering with activities in the past 24 hr (P = 0.02) in the short sleep condition than the long sleep condition. No significant differences between experimental weeks were found for weekly spirometry or exhaled nitric oxide.
conclusionsThis pilot study demonstrated the feasibility of a cross-over sleep manipulation protocol in adolescents with asthma. Since overnight decrease in PEFR is a marker of nocturnal asthma, and has been associated with the severity of daytime airflow limitation, these early-stage results suggest that shortened sleep duration may exacerbate adolescent asthma and associated functional impairments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.