ArticleInternational journal of molecular sciences2015
Mutation breeding of extracellular polysaccharide-producing microalga Crypthecodinium cohnii by a novel mutagenesis with atmospheric and room temperature plasma.
Article in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Correction: Liu et al. Mutation Breeding of Extracellular Polysaccharide-Producing MicroalgaInternational journal of molecular sciences · 2025Article
- Mutation breeding of high-stress resistant strains for succinic acid production from corn straw.Applied microbiology and biotechnology · 2024Article
- Hyperproduction of extracellular polymeric substance in Pseudomonas fluorescens for efficient chromium (VI) absorption.Bioresources and bioprocessing · 2023Article
- Screening of antibiotics to obtain axenic cell cultures of a marine microalgaFrontiers in bioengineering and biotechnology · 2023Article
- Strain Development in Microalgal Biotechnology-Random Mutagenesis Techniques.Life (Basel, Switzerland) · 2022Review
- Exopolysaccharides from Microalgae and Cyanobacteria: Diversity of Strains, Production Strategies, and Applications.Marine drugs · 2022Review
- Screening of Cucumber Fusarium Wilt Bio-Inhibitor: High SporulationFrontiers in microbiology · 2021Article
- The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview.Marine drugs · 2019Review
- Screening of a highly inhibitor-tolerant bacterial strain for 2,3-BDO and organic acid production from non-detoxified corncob acid hydrolysate.AMB Express · 2019Article
- Novel breeding approach for Japanese flounder using atmosphere and room temperature plasma mutagenesis tool.BMC genomics · 2019Article
- Effects of Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis on Physicochemical Characteristics and Immune Activity In Vitro of Hericium erinaceus Polysaccharides.Molecules (Basel, Switzerland) · 2019Article
- Elevated H2AX Phosphorylation Observed with kINPen Plasma Treatment Is Not Caused by ROS-Mediated DNA Damage but Is the Consequence of Apoptosis.Oxidative medicine and cellular longevity · 2019Article
- The Anti-Inflammatory Effect and Structure of EPCP1-2 from Crypthecodinium cohnii via Modulation of TLR4-NF-κB Pathways in LPS-Induced RAW 264.7 Cells.Marine drugs · 2017Article
- Extracellular Metabolites from Industrial Microalgae and Their Biotechnological Potential.Marine drugs · 2016Review
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracellular polysaccharides (EPS) produced by marine microalgae have the potential to be used as antioxidants, antiviral agents, immunomodulators, and anti-inflammatory agents. Although the marine microalga Crypthecodinium cohnii releases EPS during the process of docosahexaenoic acid (DHA) production, the yield of EPS remains relatively low. To improve the EPS production, a novel mutagenesis of C. cohnii was conducted by atmospheric and room temperature plasma (ARTP). Of the 12 mutants obtained, 10 mutants exhibited significantly enhanced EPS yield on biomass as compared with the wild type strain. Among them, mutant M7 was the best as it could produce an EPS volumetric yield of 1.02 g/L, EPS yield on biomass of 0.39 g/g and EPS yield on glucose of 94 mg/g, which were 33.85%, 85.35% and 57.17% higher than that of the wild type strain, respectively. Results of the present study indicated that mutagenesis of the marine microalga C. cohnii by ARTP was highly effective leading to the high-yield production of EPS.
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