Evidence map›Paper›PMID 25870853›Full record

ArticleFrontiers in chemistry2015

The association constant of 5',8-cyclo-2'-deoxyguanosine with cytidine.

Amedeo Capobianco, Tonino Caruso, Sandra Fusco, Michael A Terzidis, Annalisa Masi, Chryssostomos Chatgilialoglu, Andrea Peluso

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Dynamics of Hole Transfer in DNA.Molecules (Basel, Switzerland) · 2019
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amedeo CapobiancoDipartimento di Chimica e Biologia, Università di Salerno Fisciano, Salerno, Italy.
Tonino CarusoDipartimento di Chimica e Biologia, Università di Salerno Fisciano, Salerno, Italy.
Sandra FuscoDipartimento di Chimica e Biologia, Università di Salerno Fisciano, Salerno, Italy.
Michael A TerzidisIstituto per la Sintesi Organica e la Fotoreattività, Consiglio Nazionale delle Ricerche Bologna, Italy.
Annalisa MasiIstituto per la Sintesi Organica e la Fotoreattività, Consiglio Nazionale delle Ricerche Bologna, Italy.
Chryssostomos ChatgilialogluIstituto per la Sintesi Organica e la Fotoreattività, Consiglio Nazionale delle Ricerche Bologna, Italy ; Institute of Nanoscience and Nanotechnology, National Center for Scientific Research "Demokritos," Athens, Greece.
Andrea PelusoDipartimento di Chimica e Biologia, Università di Salerno Fisciano, Salerno, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association of 5',8-cyclo-2'-deoxyguanosine (cdG), a DNA tandem lesion, with its complementary base cytosine has been studied by voltammetry and NMR in chloroform, using properly silylated derivatives of the two nucleobases for increasing their solubilities. Both voltammetric data and NMR titrations indicated that the Watson-Crick complex of cytidine with cdG is weaker than that with guanosine, the difference being approximately of one order of magnitude between the two association constants.

Indexed as

cyclopurinesDNA damageNMRvoltammetryWatson-Crick complex

Identifiers

PMID25870853
PMCPMC4376000

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.