Evidence map›Paper›PMID 25870739›Full record

ArticleThe Pan African medical journal2014

High IgE sensitization to maize and rice pollen in the highlands of Madagascar.

Ramavovololona, Hélène Sénéchal, Ange Andrianarisoa, Vololona Rakotoarimanana, Dominique Godfrin, Gabriel Peltre, Pascal Poncet, Jean-Pierre Sutra

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Allergic Anaphylactic Risk in Farming Activities: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

RamavovololonaSciences University, Biology and Plant Ecology Department, BP 906, Antananarivo 101, Madagascar.
Hélène SénéchalArmand Trousseau Children's Hospital, Biochemistry Department, Allergy & Environment, 26 avenue du Dr Arnold Netter, 75571 Paris cedex 12, France ; Inserm, 101 rue de Tolbiac, 75013 Paris, France.
Ange AndrianarisoaMedical University, Medecine and Medical Specialities Department, BP 375, Antananarivo 101, Madagascar.
Vololona RakotoarimananaSciences University, Biology and Plant Ecology Department, BP 906, Antananarivo 101, Madagascar.
Dominique GodfrinLaboratory of Scientific Police, 31 Avenue Franklin Roosevelt, 69130, Ecully, France.
Gabriel PeltreArmand Trousseau Children's Hospital, Biochemistry Department, Allergy & Environment, 26 avenue du Dr Arnold Netter, 75571 Paris cedex 12, France ; CNRS, 75794, Paris cedex 16, France.
Pascal PoncetArmand Trousseau Children's Hospital, Biochemistry Department, Allergy & Environment, 26 avenue du Dr Arnold Netter, 75571 Paris cedex 12, France ; Pasteur Institute, Infections & Epidemiology Department, 25-28 rue du Dr Roux, 75724, Paris cedex 15, France.
Jean-Pierre SutraArmand Trousseau Children's Hospital, Biochemistry Department, Allergy & Environment, 26 avenue du Dr Arnold Netter, 75571 Paris cedex 12, France.
Boston Children's Museum · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMaize and rice are two crops constituting the main food supply in many under-developed and developing countries. Despite the large area devoted to the culture, the sensitization to the pollen from these plants is reported to be low and often considered as an occupational allergy.

methodsSixty five Malagasy pollen allergic patients were clinically and immunochemically investigated with regard to maize and rice pollen allergens. Pollen extracts were electrophoretically separated in 1 and 2 dimensions and IgE and IgG reactivities detected upon immunoblotting.

resultsWhen exploring the sensitization profile of Malagasy allergic patients to maize and rice pollen, it appears that a high proportion of these patients consulting during grass pollinating season were sensitized to both pollen as revealed by skin prick testing (62 vs. 59%) and IgE immunoblotting (85 vs. 40%). Several clinically relevant allergens were recognized by patients' serum IgE in maize and rice pollen extracts.

conclusionThe high levels of maize and rice pollen sensitization should be related, in this tropical region, to a specific environmental exposure including i) a proximity of the population to the allergenic sources and ii) a putative exacerbating effect of a highly polluted urban atmosphere on pollen allergenicity. Cross-reactivities between wild and cultivated grasses and also between rice and maize pollen are involved as well as some specific maize sensitizations. The presence of dense urban and peri-urban agriculture, in various African regions and worldwide, could be a high environmental risk factor for people sensitive to maize pollen.

Indexed as

AdolescentAdultAgedAllergensChildChild, PreschoolFemaleHumansImmunoblottingImmunoglobulin EImmunoglobulin GMadagascarMaleMiddle AgedOryzaPollenAllergensImmunoglobulin EImmunoglobulin GIgE binding proteinsMadagascarmaizepollen allergyriceurban and peri-urban agriculture

Identifiers

PMID25870739
PMCPMC4391898
OpenAlexW2022914171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.