Evidence map›Paper›PMID 25870641›Full record

ArticleThe journal of Tehran Heart Center2014

Comparison between QT Interval Parameters in Type 2 Diabetic and Nondiabetic Patients with Non-ST Elevation Myocardial Infarction.

Hamid Reza Bonakdar, Masoumeh Aslanpour, Hassan Moladoust, Parham Sadeghipour, Fereshteh Mohamadi, Mohammad Assadian Rad, Jalal Kheirkhah

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in The journal of Tehran Heart Center, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hamid Reza BonakdarHeshmat Cardiovascular Medical Center, Guilan University of Medical Sciences, Rasht, Iran.
Masoumeh AslanpourHeshmat Cardiovascular Medical Center, Guilan University of Medical Sciences, Rasht, Iran.
Hassan MoladoustCardiovascular Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Parham SadeghipourHeshmat Cardiovascular Medical Center, Guilan University of Medical Sciences, Rasht, Iran.
Fereshteh MohamadiRazi General Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Mohammad Assadian RadHeshmat Cardiovascular Medical Center, Guilan University of Medical Sciences, Rasht, Iran.
Jalal KheirkhahHeshmat Cardiovascular Medical Center, Guilan University of Medical Sciences, Rasht, Iran.
Guilan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQT interval parameters have been suggested as a predictor of lethal arrhythmia and mortality in patients with myocardial infarction. The aim of the present study was to compare the value of QT interval indices in patients presenting with non-ST-segment elevation myocardial infarction (NSTEMI) between a group of patients with type 2 diabetes mellitus and a nondiabetic group of patients.

methodsThis case-control study evaluated QT interval parameters in 115 patients (47 diabetic and 68 nondiabetic patients) diagnosed with NSTEMI between September 2011 and July 2012. The following QT interval indices were analyzed: maximum (max) and minimum (min) QT interval; max and min corrected QT interval (QTc); QT dispersion (QTd); and corrected QT dispersion (QTcd). All the patients were observed for ventricular arrhythmia during their hospital course and underwent coronary angiography. They were selected to undergo coronary artery bypass surgery (CABG) or percutaneous coronary angioplasty (PCI) based on their coronary anatomy.

resultsThe mean age of the patients was 60.8 ± 11.4 years. The patients were 40.0% female and 60.0% male. There were no significant differences in clinical characters between type 2 diabetic and nondiabetic patients with NSTEMI. Compared with post-myocardial infarction patients without diabetes, those with type 2 diabetes had higher QTc max, QTd and QTcd (p value < 0.05). There was a significant difference in QTd and QTcd in the patients needing coronary revascularization with diabetes as opposed to the nondiabetics (p value = 0.035 and p value = 0.025, respectively) as well as those who had ventricular arrhythmia with diabetes (p value = 0.018 and p value = 0.003, respectively). QTcd was higher in the patients who had higher in-hospital mortality (p value = 0.047). The QTc max, QTd and QTcd were significantly (all p values < 0.05) associated with ventricular arrhythmia, QTcd with need for revascularization and QTc max with in-hospital mortality in the diabetic patients.

conclusionBased on the findings of this study, it seems that type 2 diabetics with NSTEMI have greater QTc max, QTd, and QTcd and these QT parameters may have a relationship with worse cardiac outcomes and poorer prognoses.

Indexed as

Diabetes mellitus, type 2ElectrocardiographyMyocardial infarction

Identifiers

PMID25870641
PMCPMC4394055
OpenAlexW2240787971

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.