ArticleJournal of geriatric cardiology : JGC2015
Associations between serum potassium and sodium levels and risk of hypertension: a community-based cohort study.
Article in Journal of geriatric cardiology : JGC, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Potassium Intake and Blood Pressure: A Dose-Response Meta-Analysis of Randomized Controlled Trials.Journal of the American Heart Association · 2020Pooled it
- Meta-Analysis of Potassium Intake and the Risk of Stroke.Journal of the American Heart Association · 2016Pooled it
- Serum potassium and sodium levels and nutrient intake in population exposed to radiation from the Semipalatinsk nuclear test site.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Simple methods for estimating the maximum 24-hour urinary potassium excretion in kidney failure without replacement therapy patients.Renal failure · 2025Article
- Association of serum levels and intakes of sodium and potassium with hypertension in the MASHAD cohort study population: a cross-sectional study.Journal of health, population, and nutrition · 2025Article
- Risk factors for lenvatinib-induced hypertension in patients with hepatocellular carcinoma: A retrospective study.British journal of clinical pharmacology · 2025Article
- Macrophage SPAK deletion limits a low potassium-induced kidney inflammatory program.American journal of physiology. Renal physiology · 2024Article
- USING SIMULTANEOUS REGRESSION CALIBRATION TO STUDY THE EFFECT OF MULTIPLE ERROR-PRONE EXPOSURES ON DISEASE RISK UTILIZING BIOMARKERS DEVELOPED FROM A CONTROLLED FEEDING STUDY.The annals of applied statistics · 2024Article
- Prediction Tool to Estimate Potassium Diet in Chronic Kidney Disease Patients Developed Using a Machine Learning Tool: The UniverSel Study.Nutrients · 2022Article
- Serum sodium and risk of hypertension: a cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Impact of Micronutrients on Hypertension: Evidence from Clinical Trials with a Special Focus on Meta-Analysis.Nutrients · 2021Review
- Identification of calcium, sodium, magnesium and chloride ion levels in hypertensive and non-hypertensive trinidadians.International journal of biochemistry and molecular biology · 2019Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSeveral studies have examined the relationships between dietary potassium and sodium and hypertension, but few have evaluated the association between serum potassium or sodium and risk of incident hypertension. We therefore investigated the associations between serum potassium and sodium and risk of incident hypertension in a Chinese community-based population.
methodsA total of 839 normotensive individuals without cardiovascular disease from the Chinese Multi-Provincial Cohort Study who took part in the baseline examination in 2007-2008 and the follow-up survey in 2012-2013 were included in this study. Odds ratios (OR) and 95% confidence intervals (95%CI) for baseline serum potassium and sodium in relation to the risk of new-onset hypertension were evaluated using multivariate logistic regression models.
resultsDuring five years of follow-up, 218 (26.0%) individuals progressed to hypertension. Logistic regression adjusting for multiple confounders showed that every 1 mEq/L increment in baseline serum potassium level was associated with a 75% increased risk of hypertension (OR: 1.75; 95%CI: 1.01-3.04; P = 0.04). Compared with adults with serum potassium level of 4.20-4.79 mEq/L, adults with level ≥ 4.80 mEq/L had an 84% increased risk of hypertension (OR: 1.84; 95%CI: 1.14-2.96; P = 0.01). There was no significant association between serum sodium and risk of hypertension (OR: 0.96; 95%CI: 0.89-1.04; P = 0.33).
conclusionsBaseline serum potassium level, but not baseline serum sodium level, was positively related to the risk of incident hypertension in the Chinese population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.