Evidence map›Paper›PMID 25870512›Full record

ReviewInfection and drug resistance2015

Lymphogranuloma venereum: diagnostic and treatment challenges.

Romana Ceovic, Sandra Jerkovic Gulin

Open access · goldAbstract readReview
In one paragraph

Review in Infection and drug resistance, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 95 citations in OpenAlex.

  1. Plasmid-encoded Pgp3 protein enhances the infectivity ofZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
  2. Article
  3. Genes · 2025
    Review
  4. Prevalence and Genetic Characterization ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  5. Article
  6. Review
  7. ThemBio · 2023
    Article
  8. Article
  9. Microorganisms · 2023
    Review
  10. Article
  11. The role of infected epithelial cells inFrontiers in cellular and infection microbiology · 2023
    Review
  12. Article
  13. Genital ulcer disease: A review.Journal of family medicine and primary care · 2022
    Review
  14. TheInfection and immunity · 2022
    Article
  15. Lymphogranuloma venereum: an emerging problem in Poland.Postepy dermatologii i alergologii · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Diagnosis and management of hidradenitis suppurativa in women.American journal of obstetrics and gynecology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Romana CeovicDepartment of Dermatology and Venereology, University Hospital Center Zagreb and School of Medicine, Zagreb, Croatia.
Sandra Jerkovic GulinDepartment of Dermatology and Venereology, General Hospital Sibenik, Sibenik, Croatia.
Polytechnics of Šibenik · HRUniversity Hospital Centre Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphogranuloma venereum is a sexually transmitted disease caused by L1, L2, and L3 serovars of Chlamydia trachomatis. In the last 10 years outbreaks have appeared in North America, Europe, and Australia in the form of proctitis among men who have sex with men. Three stages of disease have been described. The disease in primary stage may go undetected when only a painless papule, pustule, or ulceration appears. The diagnosis is difficult to establish on clinical grounds alone and frequently relies upon either serologic testing, culture, or more recently, nucleic acid amplification testing of direct specimens. A proper treatment regimen cures the infection and prevents further damage to tissues. Lymphogranuloma venereum causes potentially severe infections with possibly irreversible sequels if adequate treatment is not begun promptly. Early and accurate diagnosis is essential. Doxycycline is the drug of choice. Pregnant and lactating women should be treated with erythromycin or azithromycin. Patient must be followed up during the treatment, until disease signs and symptoms have resolved. Repeated testing for syphilis, hepatitis B and C, and HIV to detect early infection should be performed.

Indexed as

Chlamydia trachomatisearly and accurate diagnosissexually transmitted disease

Identifiers

PMID25870512
PMCPMC4381887
OpenAlexW2025061640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.