Evidence map›Paper›PMID 25870419›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Serological investigation of heartland virus (Bunyaviridae: Phlebovirus) exposure in wild and domestic animals adjacent to human case sites in Missouri 2012-2013.

Angela M Bosco-Lauth, Nicholas A Panella, J Jeffrey Root, Tom Gidlewski, R Ryan Lash, Jessica R Harmon, Kristen L Burkhalter, Marvin S Godsey, Harry M Savage, William L Nicholson and 2 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

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  14. A panel of real-time PCR assays for the detection of Bourbon virus, Heartland virus, West Nile virus, andJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
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  17. Heartland Virus in Lone Star Ticks, Alabama, USA.Emerging infectious diseases · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Angela M Bosco-LauthDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Nicholas A PanellaDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
J Jeffrey RootDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Tom GidlewskiDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
R Ryan LashDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jessica R HarmonDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Kristen L BurkhalterDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Marvin S GodseyDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Harry M SavageDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
William L NicholsonDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Nicholas KomarDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Aaron C BraultDivision of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado; Division of Vector-Borne Diseases, Rickettsial Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia abrault@cdc.gov.
Animal and Plant Health Inspection Service · USCenters for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heartland virus (HRTV; Bunyaviridae: Phlebovirus) has recently emerged as a causative agent of human disease characterized by thrombocytopenia and leukopenia in the United States. The lone star tick (Amblyomma americanum L.) has been implicated as a vector. To identify candidate vertebrate amplification hosts associated with enzootic maintenance of the virus, sera and ticks were sampled from 160 mammals (8 species) and 139 birds (26 species) captured near 2 human case residences in Andrew and Nodaway Counties in northwest Missouri. HRTV-specific neutralizing antibodies were identified in northern raccoons (42.6%), horses (17.4%), white-tailed deer (14.3%), dogs (7.7%), and Virginia opossums (3.8%), but not in birds. Virus isolation attempts from sera and ticks failed to detect HRTV. The high antibody prevalence coupled with local abundance of white-tailed deer and raccoons identifies these species as candidate amplification hosts.

Indexed as

PhlebovirusAnimalsAnimals, DomesticAnimals, WildBirdsBunyaviridae InfectionsDeerDidelphisDisease VectorsHorsesHumansMissouriNeutralization TestsRaccoonsTicksZoonoses

Identifiers

PMID25870419
PMCPMC4458820
OpenAlexW2153402644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.