Impact on outcome of delayed intubation with high-flow nasal cannula oxygen: is the device solely responsible?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

1. Comparing high-flow nasal cannula oxygen and non-invasive ventilation to standard oxygenation in non-selected intensive care unit patients admitted for acute hypoxaemic respiratory failure: protocol for the KISS (Key oxygenation Interventions in Surgical and non-Surgical patients) adaptive randomised controlled trial.BMJ open · 2025
   Article
2. Non-Invasive Positive Pressure Ventilation for Pre-Oxygenation of Critically Ill Patients Before Intubation.Journal of clinical medicine · 2025
   Review
3. The Clinical Effect of High-Flow Oxygen Therapy through the Nose on Patients with Acute Left Heart Failure and Hypoxemia.Journal of healthcare engineering · 2022
   Article
4. Supplementation of High Velocity Nasal Insufflation with a Nonrebreather Mask for Severe Hypoxemic Respiratory Failure in Adult Patients with COVID-19.Case reports in critical care · 2022
   Article
5. [Clinical experience of high-flow nasal cannula oxygen therapy in severe COVID-19 patients].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2020
   Article
6. The role of a critical care outreach service in the management of patients with haematological malignancy.Journal of the Intensive Care Society · 2019
   Article
7. Nasal high flow: physiology, efficacy and safety in the acute care setting, a narrative review.Open access emergency medicine : OAEM · 2019
   Article
8. High-flow nasal cannula to prevent postextubation respiratory failure in high-risk non-hypercapnic patients: a randomized multicenter trial.Annals of intensive care · 2017
   Article
9. Use of high-flow nasal cannula oxygenation in ICU adults: a narrative review.Intensive care medicine · 2016
   Review
10. Current evidence for the effectiveness of heated and humidified high flow nasal cannula supportive therapy in adult patients with respiratory failure.Critical care (London, England) · 2016
    Review

Corrections and comments

• Comment on
  Failure of high-flow nasal cannula therapy may delay intubation and increase mortality.2015

Authors and funding

4 authors at 3 institutions in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as