Evidence map›Paper›PMID 25868906›Full record

ArticleJournal of the American Society for Mass Spectrometry2015

Charge Detection Mass Spectrometry for Single Ions with an Uncertainty in the Charge Measurement of 0.65 e.

Elizabeth E Pierson, Nathan C Contino, David Z Keifer, Martin F Jarrold

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Thermal Remodeling of Human HDL Particles Reveals Diverse Subspecies.Journal of the American Society for Mass Spectrometry · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Ion-Ion Interactions in Charge Detection Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2019
    Article
  14. Article
  15. Article
  16. Real-Time Analysis and Signal Optimization for Charge Detection Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2019
    Article
  17. Article
  18. Article
  19. Optimized Electrostatic Linear Ion Trap for Charge Detection Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elizabeth E PiersonChemistry Department, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN, 47405, USA.
Nathan C Contino
David Z Keifer
Martin F Jarrold

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Charge detection mass spectrometry (CDMS) provides a direct measure of the mass of individual ions through nondestructive, simultaneous measurements of the mass to charge ratio and the charge. To improve the accuracy of the charge measurement, ions are trapped and recirculated through the charge detector. By substantially extending the trapping time, the uncertainty in the charge determination has been reduced by a factor of two, from 1.3 elementary charges (e) to 0.65 e. The limit of detection (the smallest charge that can be reliably measured) has been reduced by about the same proportion, from 13 to 7 e. The more precise charge measurements enable a substantial improvement in the mass resolution, which is critical for applications of CDMS to mixtures of high mass ions.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.