ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2015
Precision and accuracy of clinical quantification of myocardial blood flow by dynamic PET: A technical perspective.
Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Feasibility of dynamic stressEuropean journal of nuclear medicine and molecular imaging · 2018Trial
- Comparison among Reconstruction Algorithms for Quantitative Analysis ofContrast media & molecular imaging · 2018Trial
- Preliminary protocol for measuring the reproducibility and accuracy of flow values on digital PET/CT systems in [EJNMMI physics · 2024Article
- Integrated myocardial flow reserve (iMFR) assessment: diffuse atherosclerosis and microvascular dysfunction are more strongly associated with mortality than focally impaired perfusion.European journal of nuclear medicine and molecular imaging · 2023Article
- SPECT measurements of myocardial blood flow and flow reserve: from development to implementation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- A retrospective evaluation of Bayesian-penalized likelihood reconstruction for [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Effect of temporal sampling protocols on myocardial blood flow measurements using Rubidium-82 PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Assessment of a digital and an analog PET/CT system for accurate myocardial perfusion imaging with a flow phantom.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Are we good enough in the evaluation of MPI using Rubidium82 with PMT PET/CT? A comparison to SiPM PET/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Effects of two patient-specific dosing protocols on measurement of myocardial blood flow with 3DEuropean journal of nuclear medicine and molecular imaging · 2021Article
- Assessment of motion correction in dynamic rubidium-82 cardiac PET with and without frame-by-frame adjustment of attenuation maps for calculation of myocardial blood flow.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Optimizing accuracy and precision with motion correction of PET myocardial blood flow measurements.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.European journal of nuclear medicine and molecular imaging · 2021Article
- Quantitative clinical nuclear cardiology, part 2: Evolving/emerging applications.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Review
- Letter to the editor: Lassen et al. 3D PET/CTEuropean journal of nuclear medicine and molecular imaging · 2020Article
- Multiparametric CardiacIEEE transactions on radiation and plasma medical sciences · 2020Article
- How to detect and correct myocardial creep in myocardial perfusion imaging using Rubidium-82 PET?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Myocardial Creep: we can now look it in the eye without framewise PET-CT registration for myocardial blood flow quantification.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- The potential for PET-guided revascularization of coronary artery disease.European journal of nuclear medicine and molecular imaging · 2019Article
- The utility ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
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Authors and funding
5 authors.
Funding
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Abstract
A number of exciting advances in PET/CT technology and improvements in methodology have recently converged to enhance the feasibility of routine clinical quantification of myocardial blood flow and flow reserve. Recent promising clinical results are pointing toward an important role for myocardial blood flow in the care of patients. Absolute blood flow quantification can be a powerful clinical tool, but its utility will depend on maintaining precision and accuracy in the face of numerous potential sources of methodological errors. Here we review recent data and highlight the impact of PET instrumentation, image reconstruction, and quantification methods, and we emphasize (82)Rb cardiac PET which currently has the widest clinical application. It will be apparent that more data are needed, particularly in relation to newer PET technologies, as well as clinical standardization of PET protocols and methods. We provide recommendations for the methodological factors considered here. At present, myocardial flow reserve appears to be remarkably robust to various methodological errors; however, with greater attention to and more detailed understanding of these sources of error, the clinical benefits of stress-only blood flow measurement may eventually be more fully realized.
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