ArticleNature reviews. Neurology2015
Epilepsy: closing the loop for patients with epilepsy.
Article in Nature reviews. Neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Multifunctional hydrogel electronics for closed-loop antiepileptic treatment.Science advances · 2024Article
- The critical dynamics of hippocampal seizures.Nature communications · 2024Article
- Spike patterns surrounding sleep and seizures localize the seizure-onset zone in focal epilepsy.Epilepsia · 2023Article
- Flexible Electronics and Devices as Human-Machine Interfaces for Medical Robotics.Advanced materials (Deerfield Beach, Fla.) · 2022Review
- Neuromodulation Strategies to Reduce Inflammation and Improve Lung Complications in COVID-19 Patients.Frontiers in neurology · 2022Review
- Deep brain stimulation in the medial septum attenuates temporal lobe epilepsy via entrainment of hippocampal theta rhythm.CNS neuroscience & therapeutics · 2021Article
- The Effectiveness of Vagus Nerve Stimulation in Drug-Resistant Epilepsy Correlates with Vagus Nerve Stimulation-Induced Electroencephalography Desynchronization.Brain connectivity · 2020Article
- Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset.Brain : a journal of neurology · 2020Article
- Closed Loop Deep Brain Stimulation for PTSD, Addiction, and Disorders of Affective Facial Interpretation: Review and Discussion of Potential Biomarkers and Stimulation Paradigms.Frontiers in neuroscience · 2018Review
- Mechanisms underlying different onset patterns of focal seizures.PLoS computational biology · 2017Article
- Innervation of the Human Cavum Conchae and Auditory Canal: Anatomical Basis for Transcutaneous Auricular Nerve Stimulation.BioMed research international · 2017Article
- Electroresponsive Nanoparticles Improve Antiseizure Effect of Phenytoin in Generalized Tonic-Clonic Seizures.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a long-term clinical trial, a responsive neurostimulation system was shown to reduce seizures and improve quality of life in patients with drug-resistant epilepsy. Furthermore, these effects persisted over an extended time period. Will neurostimulation close the treatment gap for patients with refractory epilepsy?
Indexed as
Identifiers
25868392What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.