Evidence map›Paper›PMID 25867447›Full record

Trial reportJournal of consulting and clinical psychology2015

Paths to tobacco abstinence: A repeated-measures latent class analysis.

Danielle E McCarthy, Lemma Ebssa, Katie Witkiewitz, Saul Shiffman

Open access · hybridAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Dyadic patterns of abstinence from smoking in dual-smoking couples enrolled in a pilot randomized clinical trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Article
  12. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Discontinuous Patterns of Cigarette Smoking From Ages 18 to 50 in the United States: A Repeated-Measures Latent Class Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Danielle E McCarthyDepartment of Psychology, Rutgers, The State University of New Jersey.
Lemma EbssaInstitute for Health, Health Care Policy, and Aging Research, Rutgers, The State University of New Jersey.
Katie WitkiewitzDepartment of Psychology, University of New Mexico.
Saul ShiffmanDepartment of Psychology, University of Pittsburgh.
Rutgers, The State University of New Jersey · USUniversity of New Mexico · USUniversity of Pittsburgh · US

Funding

Testing Relapse Recovery Intervention ComponentsP01CA180945 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI COOK, JESSICA MEGAN · 2014 to 2023
$23.0M
Tobacco Dependence: Treatment and OutcomesP50DA019706 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI FIORE, MICHAEL C · 2004 to 2008
$8.6M
Accelerating Smoking Relapse Research Using Longitudinal Models of EMA DataR01DA033303 · NIDA · RUTGERS, THE STATE UNIV OF N.J. · PI MCCARTHY, DANIELLE ERIN, SHIFFMAN, SAUL · 2012 to 2014
$676k
NCI NIH HHS P01 CA180945NIDA NIH HHS 5P50DA019706NIDA NIH HHS P50 DA019706NIDA NIH HHS R01 DA033303NIDA NIH HHS R01DA033303
6 · The paper itself

Abstract

objectiveKnowledge of smoking change processes may be enhanced by identifying pathways to stable abstinence. We sought to identify latent classes of smokers based on their day-to-day smoking status in the first weeks of a cessation attempt. We examined treatment effects on class membership and compared classes on baseline individual differences and 6-month abstinence rates.

methodIn this secondary analysis of a double-blind randomized placebo-controlled clinical trial (N = 1,433) of 5 smoking cessation pharmacotherapies (nicotine patch, nicotine lozenge, bupropion SR, patch and lozenge, or bupropion SR and lozenge), we conducted repeated-measures latent class analysis of daily smoking status (any smoking vs. none) for the first 27 days of a quit attempt. Treatment and covariate relations with latent class membership were examined. Distal outcome analysis compared confirmed 6-month abstinence rates among the latent classes.

resultsA 5-class solution was selected. Three-quarters of smokers were in stable smoking or abstinent classes, but 25% were in classes with unstable abstinence probabilities over time. Active treatment (compared to placebo), and particularly the patch and lozenge combination, promoted early quitting. Latent classes differed in 6-month abstinence rates and on several baseline variables, including nicotine dependence, quitting history, self-efficacy, sleep disturbance, and minority status.

conclusionsRepeated-measures latent class analysis identified latent classes of smoking change patterns affected by treatment, related to known risk factors, and predictive of distal outcomes. Tracking behavior early in a change attempt may identify prognostic patterns of change and facilitate adaptive treatment planning.

Indexed as

Smoking CessationTobacco Use Cessation DevicesAdultBupropionDopamine Uptake InhibitorsDouble-Blind MethodFemaleHumansMaleMiddle AgedNicotineNicotinic AgonistsSmokingTobacco Use DisorderTreatment OutcomeBupropionDopamine Uptake InhibitorsNicotineNicotinic Agonists

Identifiers

PMID25867447
PMCPMC4516640
OpenAlexW2323011252

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.