ArticleJundishapur journal of natural pharmaceutical products2015
Enhancement of human skin fibroblasts proliferation as a result of treating with quince seed mucilage.
Article in Jundishapur journal of natural pharmaceutical products, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Design of multiple-function matrix encapsulated with Marjoram extract to support cellular functions, stimulate collagen synthesis and decrease infection in wound.Scientific reports · 2024Article
- Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from NineAntioxidants (Basel, Switzerland) · 2023Article
- Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals.Molecules (Basel, Switzerland) · 2021Review
- Protective Effects ofIranian journal of pharmaceutical research : IJPR · 2020Article
- Effect of the topical application of an ethanol extract of quince seeds on the development of atopic dermatitis-like symptoms in NC/Nga mice.BMC complementary and alternative medicine · 2017Article
- Cydonia oblonga M., A Medicinal Plant Rich in Phytonutrients for Pharmaceuticals.Frontiers in pharmacology · 2016Review
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Authors and funding
3 authors.
Funding
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Abstract
backgroundQuince seed mucilage (QSM) has been used in Iranian folk medicine in the treatment of wounds and burns. Experimental and clinical studies showed its wound healing activity. However, the mechanism by which this agent affects cells involved in the wound healing process is unknown.
objectivesIn this study, we investigated the effects of QSM at concentrations of 50, 100, 200, and 400 µg/mL on human skin fibroblast proliferation as an aspect of promotion of wound healing. MATERIALS AND
methodsHuman skin fibroblast cell line (HNFF-P18) was used in the experiment. Cell proliferation assay was measured by a MTT assay.
resultsCells treated with QSM at concentrations less than 400 µg/mL increased their proliferative activity. The concentration of 50 µg/mL was the most effective dose after 72 hours treatment.
conclusionsQSM has the ability to stimulate proliferation of human skin fibroblast. This effect suggests that this compound can act as a wound healing agent.
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