ReviewIUCrJ2015
Synchrotron radiation macromolecular crystallography: science and spin-offs.
Review in IUCrJ, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Where and how to house big data on small fragments.Nature communications · 2025Review
- Current and future perspectives for structural biology at the Grenoble EPN campus: a comprehensive overview.Journal of synchrotron radiation · 2025Review
- Macromolecular crystallography from an industrial perspective - the impact of synchrotron radiation on structure-based drug discovery.Journal of synchrotron radiation · 2025Article
- Metal-Based Drug-DNA Interactions and Analytical Determination Methods.Molecules (Basel, Switzerland) · 2024Review
- A capillary-based microfluidic device enables primary high-throughput room-temperature crystallographic screening.Journal of applied crystallography · 2021Article
- Synchrotron Radiation as a Tool for Macromolecular X-Ray Crystallography: a XXI Century Perspective.Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms · 2021Article
- Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.bioRxiv : the preprint server for biology · 2020Article
- Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease.Nature communications · 2020Article
- Perspectives on single particle imaging with x rays at the advent of high repetition rate x-ray free electron laser sources.Structural dynamics (Melville, N.Y.) · 2020Article
- Molecular methods for assessment of non-covalent metallodrug-DNA interactions.Chemical Society reviews · 2019Review
- Review
- Rapid cadmium SAD phasing at the standard wavelength (1 Å).Acta crystallographica. Section D, Structural biology · 2017Article
- A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.Nature communications · 2017Article
- Synchrotron-based macromolecular crystallography module for an undergraduate biochemistry laboratory course.Journal of applied crystallography · 2016Article
- Data publication with the structural biology data grid supports live analysis.Nature communications · 2016Article
- Widening the reach of structural biology.IUCrJ · 2016Article
- Serial femtosecond crystallography opens new avenues for Structural Biology.Protein and peptide letters · 2016Article
- Crystallography is more than crystal structures.IUCrJ · 2015Article
- Protein Crystallography in Vaccine Research and Development.International journal of molecular sciences · 2015Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A current overview of synchrotron radiation (SR) in macromolecular crystallography (MX) instrumentation, methods and applications is presented. Automation has been and remains a central development in the last decade, as have the rise of remote access and of industrial service provision. Results include a high number of Protein Data Bank depositions, with an increasing emphasis on the successful use of microcrystals. One future emphasis involves pushing the frontiers of using higher and lower photon energies. With the advent of X-ray free-electron lasers, closely linked to SR developments, the use of ever smaller samples such as nanocrystals, nanoclusters and single molecules is anticipated, as well as the opening up of femtosecond time-resolved diffraction structural studies. At SR sources, a very high-throughput assessment for the best crystal samples and the ability to tackle just a few micron and sub-micron crystals will become widespread. With higher speeds and larger detectors, diffraction data volumes are becoming long-term storage and archiving issues; the implications for today and the future are discussed. Together with the rise of the storage ring to its current pre-eminence in MX data provision, the growing tendency of central facility sites to offer other centralized facilities complementary to crystallography, such as cryo-electron microscopy and NMR, is a welcome development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.