Evidence map›Paper›PMID 25866567›Full record

ReviewJournal of medicine and life

Controversies in the diagnosis and treatment of early cutaneous melanoma.

O A Orzan, A Șandru, C R Jecan

Abstract readReview
In one paragraph

Review in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Non-coding RNA profiling in BRAFScientific data · 2025
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  3. Gels (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

O A Orzan"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; Department of Dermatology, Elias University Emergency Hospital, Bucharest, Romania.
A Șandru"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; Department of Surgical Oncology, "Alexandru Trestioreanu" Oncologic Institute, Bucharest, Romania.
C R Jecan"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; Department of Plastic and Reconstructive Microsurgery, "Prof. Dr. Agrippa Ionescu" Clinical Emergency Hospital, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous melanoma (CM) is a disease with an unpredictable evolution mainly due to its high metastatic ability. The steadily increasing incidence and the poor outcome in advanced stages made this cancer an interesting field for many research groups. Given that CM is a curable disease in early stages, efforts have been made to detect it as soon as possible, which led to the diversification and refining of diagnosis methods and therapies. But, as the data from trials have been published, doubts about the indications and efficacy of established treatments have arisen. In fact, there is probably no single aspect of early CM that has not given birth to controversy. This article intends to present the current disputes regarding the early detection, diagnosis, treatment and postoperative follow-up of patients with localized CM. After analyzing both pros and cons, several conclusions were drawn, that reflect our experience in managing patients with early CM.

Indexed as

Cutaneous Malignant MelanomaDermoscopyHumansMelanomaPlastic Surgery ProceduresSentinel Lymph Node BiopsySkin Neoplasmsdiagnosisearly cutaneous melanomafollow-uptreatment

Identifiers

PMID25866567
PMCPMC4392104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.