Evidence map›Paper›PMID 25866548›Full record

ReviewPerspectives on psychological science : a journal of the Association for Psychological Science2015

Loneliness: clinical import and interventions.

Stephanie Cacioppo, Angela J Grippo, Sarah London, Luc Goossens, John T Cacioppo

5 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Perspectives on psychological science : a journal of the Association for Psychological Science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 476 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
476citing papers in PubMed, 10 pooled it
49.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05426837 nacompletednot on this mapstarted 2022, after this paper: background citation

Combating Social Isolation in Older Adults: Randomized Clinical Trial Evaluating the Acceptability and Efficacy of a Brief, Technology Delivered Intervention

TypeinterventionalSponsorFlorida State UniversityRan2022 to 2024Enrolled70ConditionsLoneliness, Social IsolationArmsCombatting Social Isolation, Health Education Training
NCT05764902 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Interventions to Reduce Loneliness in Elderly Patients in the Cardiac ICU (CICU): A Randomized Control Trial

TypeinterventionalSponsorPoriya Medical CenterRan2023 to 2023Enrolled60ConditionsLonelinessArmsPatient-tailored intervention
NCT05831813 nacompletednot on this mapstarted 2023, after this paper: background citation

The Feasibility, Acceptability and Preliminary Efficacy of a Group Intervention Aimed at Reducing Social and Emotional Loneliness: a Pilot Study

TypeinterventionalSponsorUniversity of AmsterdamRan2023 to 2023Enrolled9ConditionsLoneliness, Social IsolationArmsGoal-Based Cognitive Behavioural Intervention
NCT07021872 narecruitingnot on this mapstarted 2025, after this paper: background citation

Reducing Loneliness Among Older Adults Through Enhancing Positive Affect: A Randomized Controlled Trial With Ecological Momentary Assessments

TypeinterventionalSponsorEducation University of Hong KongRan2025 to 2026Enrolled276ConditionsLonelinessArmsTele-Positive Affect Intervention, Tele-Behavioral Activation Intervention, Tele-Friendly Visit
NCT07494604 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Role of Solo Music Listening in Reducing Loneliness and Increasing Social Connectedness in Older Adults

TypeinterventionalSponsorToronto Metropolitan UniversityRan2026 to 2027Enrolled120ConditionsLoneliness, Social Connectedness, Music Listening InterventionArmsMusic condition 1: Nostalgic music, Music condition 2: Comforting music, Control condition (pink-noise), Music condition 3: Distracting music
3 · Its place in the literature

Who cites it

476 citing papers in PubMed, 10 syntheses or guidelines pooled it, 1,159 citations in OpenAlex.

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416 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Stephanie CacioppoDepartment of Psychiatry and Behavioral Neuroscience, The University of Chicago ; HPEN Laboratory, Center for Cognitive and Social Neuroscience, The University of Chicago.
Angela J GrippoDepartment of Psychology, Northern Illinois University.
Sarah LondonHPEN Laboratory, Center for Cognitive and Social Neuroscience, The University of Chicago ; Department of Psychology, The University of Chicago.
Luc GoossensSchool of Psychology and Child and Adolescent Development, KU Leuven - University of Leuven.
John T CacioppoHPEN Laboratory, Center for Cognitive and Social Neuroscience, The University of Chicago ; Department of Psychology, The University of Chicago.
University of Chicago · USKU Leuven · BENorthern Illinois University · US

Funding

Social Regulation of Gene Expression, SupplementR37AG033590 · NIA · UNIVERSITY OF CHICAGO · PI CACIOPPO, JOHN T. · 2010 to 2017
$3.5M
NIA NIH HHS R37 AG033590
6 · The paper itself

Abstract

In 1978, when the Task Panel report to the US President's Commission on Mental Health emphasized the importance of improving health care and easing the pain of those suffering from emotional distress syndromes including loneliness, few anticipated that this issue would still need to be addressed 40 years later. A meta-analysis (Masi et al., 2011) on the efficacy of treatments to reduce loneliness identified a need for well-controlled randomized clinical trials focusing on the rehabilitation of maladaptive social cognition. We review assessments of loneliness and build on this meta-analysis to discuss the efficacy of various treatments for loneliness. With the advances made over the past 5 years in the identification of the psychobiological and pharmaceutical mechanisms associated with loneliness and maladaptive social cognition, there is increasing evidence for the potential efficacy of integrated interventions that combine (social) cognitive behavioral therapy with short-term adjunctive pharmacological treatments.

Indexed as

LonelinessCognitive Behavioral TherapyHumansPsychotropic DrugsPsychotropic Drugs

Identifiers

PMID25866548
PMCPMC4391342
OpenAlexW2137123520

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.