Evidence map›Paper›PMID 25865875›Full record

ArticleInternational journal of dermatology2015

A consensus approach to improving patient adherence and persistence with topical treatment for actinic keratosis.

Eggert Stockfleth, Ketty Peris, Carlos Guillen, Rino Cerio, Nicole Basset-Seguin, Peter Foley, José Sanches, Alex Culshaw, Sandra Erntoft, Mark Lebwohl

Registry-linked trialAbstract readConsensus Statement
In one paragraph

Article in International journal of dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02938715 (Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02938715 nacompletednot on this mapstarted 2016, after this paper: background citation

Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil

TypeinterventionalSponsorUniversity of California, DavisRan2016 to 2017Enrolled26ConditionsActinic KeratosisArmsteledermatology feedback
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Article
  7. Successful Treatment of Actinic Keratosis with Kanuka Honey.Case reports in dermatological medicine · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eggert StockflethKlinik für Dermatologie, Venerologie und Allergologie St. Josef-Hospital, Ruhr-Universität Bochum, Bochum, Germany.
Ketty Peris
Carlos Guillen
Rino Cerio
Nicole Basset-Seguin
Peter Foley
José Sanches
Alex Culshaw
Sandra Erntoft
Mark Lebwohl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTopical therapy is important in the treatment of actinic keratosis, but guidance for improving adherence/persistence during topical therapy is still lacking.

objectivesTo utilize expert consensus to generate a list of recommendations to improve real-world efficacy when prescribing topical therapy for actinic keratosis.

methodsAn expert panel of eight dermatologists was convened to generate recommendations based on facilitated discussion and consensus generation using a modified Delphi session. The recommendations were ratified with the expert panel.

resultsFacilitated discussion generated 31 issues within five themes, which were prioritized using expert voting. Consensus was achieved on the importance of short and simple treatment regimens for maximizing patient compliance, physician awareness of the progression of actinic keratosis to squamous cell carcinoma, provision of appropriate patient information, and the use of effective communication strategies to educate physicians about actinic keratosis. Based on these key findings, eight recommendations were generated.

conclusionsThe recommendations will assist physicians when prescribing topical actinic keratosis therapy. Further research should focus on the types of patient outcomes that are influenced by the characteristics of topical field therapy.

Indexed as

Patient ComplianceAdministration, TopicalHumansKeratosis, ActinicPractice Guidelines as Topic

Identifiers

PMID25865875
PMCPMC4437053

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.