Evidence map›Paper›PMID 25865518›Full record

ArticleEpidemiology and infection2015

Adult encephalitis surveillance: experiences from an Australian prospective sentinel site study.

K Eastwood, B J Paterson, C Levi, R Givney, M Loewenthal, T DE Malmanche, K Lai, J Granerod, D N Durrheim

Abstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

K EastwoodHunter New England Population Health,Newcastle,NSW,Australia.
B J PatersonHunter New England Population Health,Newcastle,NSW,Australia.
C LeviHunter Medical Research Institute,Newcastle,NSW,Australia.
R GivneyUniversity of Newcastle,Newcastle,NSW,Australia.
M LoewenthalUniversity of Newcastle,Newcastle,NSW,Australia.
T DE MalmancheUniversity of Newcastle,Newcastle,NSW,Australia.
K LaiUniversity of Newcastle,Newcastle,NSW,Australia.
J GranerodPublic Health England,London,UK.
D N DurrheimHunter New England Population Health,Newcastle,NSW,Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few countries routinely collect comprehensive encephalitis data, yet understanding the epidemiology of this condition has value for clinical management, detecting novel and emerging pathogens, and guiding timely public health interventions. When this study was conducted there was no standardized diagnostic algorithm to aid identification of encephalitis or systematic surveillance for adult encephalitis. In July 2012 we tested three pragmatic surveillance options aimed at identifying possible adult encephalitis cases admitted to a major Australian hospital: hospital admissions searches, clinician notifications and laboratory test alerts (CSF herpes simplex virus requests). Eligible cases underwent structured laboratory investigation and a specialist panel arbitrated on the final diagnosis. One hundred and thirteen patients were initially recruited into the 10-month study; 20/113 (18%) met the study case definition, seven were diagnosed with infectious or immune-mediated encephalitis and the remainder were assigned alternative diagnoses. The laboratory alert identified 90% (102/113) of recruited cases including six of the seven cases of confirmed encephalitis suggesting that this may be a practical data source for case ascertainment. The application of a standardized diagnostic algorithm and specialist review by an expert clinical panel aided diagnosis of patients with encephalitis.

Indexed as

Patient SelectionSentinel SurveillanceAdultAustraliaEncephalitisEncephalitis, Herpes SimplexEpidemiological MonitoringHumansInternational Classification of DiseasesProspective Studiesemerging infectious diseaseEncephalitisepidemiologysurveillance

Identifiers

PMID25865518
PMCPMC9150937

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.