Evidence map›Paper›PMID 25865249›Full record

ArticleInfluenza and other respiratory viruses2015

Evaluation of influenza vaccine effectiveness and description of circulating strains in outpatient settings in South Africa, 2014.

Johanna M McAnerney, Florette Treurnicht, Sibongile Walaza, Adam L Cohen, Stefano Tempia, Senzo Mtshali, Amelia Buys, Lucille Blumberg, Cheryl Cohen

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johanna M McAnerneyNational Institute for Communicable Diseases (NICD) , National Health laboratory services (NHLS), Johannesburg, South Africa.
Florette TreurnichtNational Institute for Communicable Diseases (NICD) , National Health laboratory services (NHLS), Johannesburg, South Africa.
Sibongile WalazaNational Institute for Communicable Diseases (NICD) , National Health laboratory services (NHLS), Johannesburg, South Africa.
Adam L CohenU.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Stefano TempiaNational Institute for Communicable Diseases (NICD) , National Health laboratory services (NHLS), Johannesburg, South Africa.
Senzo MtshaliNational Institute for Communicable Diseases (NICD) , National Health laboratory services (NHLS), Johannesburg, South Africa.
Amelia BuysNational Institute for Communicable Diseases (NICD) , National Health laboratory services (NHLS), Johannesburg, South Africa.
Lucille BlumbergNational Institute for Communicable Diseases (NICD) , National Health laboratory services (NHLS), Johannesburg, South Africa.
Cheryl CohenNational Institute for Communicable Diseases (NICD) , National Health laboratory services (NHLS), Johannesburg, South Africa.

Funding

South African Preparedness for Rapid Detection of Highly Pathogenic Avian InfluenU51IP000155 · IP · NATIONAL INST FOR COMMUNICABLE DISEASES · PI VENTER, MARIETJIE · 2007 to 2010
$6.7M
NCIRD CDC HHS U51/IP000155-04
6 · The paper itself

Abstract

The effectiveness of the trivalent seasonal influenza vaccine during the 2014 season in South Africa was assessed using a test-negative case-control study design including 472 cases and 362 controls. Influenza A(H3N2) was the dominant strain circulating. The overall vaccine effectiveness estimate, adjusted for age and underlying conditions, was 43·1% (95% CI: -26·8-74·5). 2014 H3N2 viruses from South Africa were mainly in sublineage 3C.3 with accumulation of amino acid changes that differentiate them from the vaccine strain in 3C.1.

Indexed as

AdolescentAdultCase-Control StudiesFemaleHumansInfluenza, HumanInfluenza VaccinesMaleMiddle AgedOutpatientsSeasonsSentinel SurveillanceSouth AfricaYoung AdultInfluenza VaccinesEffectivenessinfluenzavaccine

Identifiers

PMID25865249
PMCPMC4474497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.